Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 549690..550225 Replicon plasmid pC
Accession NC_010997
Organism Rhizobium etli CIAT 652

Toxin (Protein)


Gene name relE Uniprot ID B3Q5V1
Locus tag RHECIAT_RS28030 Protein ID WP_012490004.1
Coordinates 549690..549965 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F2AEZ7
Locus tag RHECIAT_RS28035 Protein ID WP_004677393.1
Coordinates 549965..550225 (-) Length 87 a.a.

Genomic Context

RHECIAT_RS28025RHECIAT_RS28040RHECIAT_RS28045RHECIAT_RS28050RHECIAT_RS28055RHECIAT_RS28010RHECIAT_RS28015RHECIAT_RS28020RHECIAT_RS28030RHECIAT_RS28035
Location: 548676..549683 (1008 bp)
Type: Others
Protein ID: WP_004677397.1
Location: 550525..551253 (729 bp)
Type: Others
Protein ID: WP_004677391.1
Location: 551544..552557 (1014 bp)
Type: Others
Protein ID: WP_012490006.1
Location: 552653..553471 (819 bp)
Type: Others
Protein ID: WP_004677388.1
Location: 553483..554364 (882 bp)
Type: Others
Protein ID: WP_012490008.1
Location: 544881..545807 (927 bp)
Type: Others
Protein ID: WP_012490002.1
Location: 545875..547095 (1221 bp)
Type: Others
Protein ID: WP_004677398.1
Location: 547145..548467 (1323 bp)
Type: Others
Protein ID: WP_012490003.1
Location: 549690..549965 (276 bp)
Type: Toxin
Protein ID: WP_012490004.1
Location: 549965..550225 (261 bp)
Type: Antitoxin
Protein ID: WP_004677393.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RHECIAT_RS28010544881..545807-927WP_012490002.1sugar ABC transporter permease-
RHECIAT_RS28015545875..547095-1221WP_004677398.1sugar ABC transporter substrate-binding protein-
RHECIAT_RS28020547145..548467-1323WP_012490003.1alpha-L-fucosidase-
RHECIAT_RS28025548676..549683+1008WP_004677397.1LacI family transcriptional regulator-
RHECIAT_RS28030549690..549965-276WP_012490004.1type II toxin-antitoxin system RelE/ParE family toxinToxin
RHECIAT_RS28035549965..550225-261WP_004677393.1ribbon-helix-helix domain-containing proteinAntitoxin
RHECIAT_RS28040550525..551253+729WP_004677391.1FadR family transcriptional regulator-
RHECIAT_RS28045551544..552557+1014WP_012490006.1ABC transporter substrate-binding protein-
RHECIAT_RS28050552653..553471+819WP_004677388.1ABC transporter ATP-binding protein-
RHECIAT_RS28055553483..554364+882WP_012490008.1ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid-virD4 / gmd1..10915231091523


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10830.44 Da        Isoelectric Point: 9.5543

>T22948 WP_012490004.1 NC_010997:c549965-549690 [Rhizobium etli CIAT 652]
MEIKWTSKAVSDIARLYDFLSPIDRRAAARTVQALAAAPARLIEQPRLGERLEEFDPQEVRRILVGRYEMRYEIQQSTIY
VLRLWHTREDR

Download         Length: 276 bp

>T22948 NC_010997:c549965-549690 [Rhizobium etli CIAT 652]
ATGGAAATCAAGTGGACGAGCAAAGCTGTCTCCGACATCGCTCGCTTATACGACTTTCTCTCCCCGATCGACCGGCGAGC
TGCGGCCCGAACCGTGCAGGCGCTGGCGGCAGCCCCCGCTCGTCTAATTGAGCAGCCACGTCTCGGCGAGCGGCTCGAAG
AGTTCGATCCTCAGGAGGTCCGCCGCATTCTCGTTGGCCGTTATGAGATGCGTTATGAAATCCAGCAGTCGACAATCTAT
GTATTGCGGCTTTGGCATACGCGCGAGGATCGGTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9686.93 Da        Isoelectric Point: 4.6135

>AT22948 WP_004677393.1 NC_010997:c550225-549965 [Rhizobium etli CIAT 652]
METKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDSGNVVDHQSVQAWADSLDGDE
PISLLR

Download         Length: 261 bp

>AT22948 NC_010997:c550225-549965 [Rhizobium etli CIAT 652]
ATGGAGACCAAAGTTCTCACGGCTCATGTTCCATTGCCGCTTGCGCAGAAGGTCGATCAGCTTGCATCGCGCCTTGAGCG
TTCGCGCGGCTGGATCGTCAAGCAAGCCCTGACTGCATGGATCGACCAGGAAGAGGAGCGTCGGCGTTTGACGCTTGAGG
CGTTAGCCGATGTGGATAGCGGCAATGTTGTCGATCACCAGTCTGTTCAAGCCTGGGCCGATAGTCTTGACGGTGACGAG
CCGATTTCGTTGCTCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7X6IWB5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2U3CQR5

References