Detailed information of TA system TA022946

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 4451890..4452451
• Replicon: chromosome
• Accession: NC_010995
• Organism: Cellvibrio japonicus Ueda107

Toxin (Protein)

• Gene name: relE
• Uniprot ID: B3PHW7
• Locus tag: CJA_RS17880
• Protein ID: WP_012489282.1
• Coordinates: 4452176..4452451 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: B3PHW6
• Locus tag: CJA_RS17875
• Protein ID: WP_012489281.1
• Coordinates: 4451890..4452159 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4444828..4554472	109644

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10722.55 Da
• Isoelectric Point: 10.1792

>T22946 WP_012489282.1 NC_010995:4452176-4452451 [Cellvibrio japonicus Ueda107]
MKIEWTTKALMDLARLYDFLAPVNQAVAARLVQQLTQAPNKLLANPRIGEKLDEFLPREVRRLLIGTYEIRYEIGNNTIY
LLRIWHTREAR

Nucleotide

• Length: 276 bp

>T22946 NC_010995:4452176-4452451 [Cellvibrio japonicus Ueda107]
ATGAAAATTGAATGGACAACCAAGGCGCTGATGGATTTGGCGCGGCTTTATGATTTCCTCGCCCCGGTCAATCAAGCAGT
GGCGGCACGCCTGGTTCAACAGCTCACCCAGGCACCAAACAAGCTGCTTGCCAATCCGCGGATTGGTGAAAAGCTGGATG
AGTTTCTACCGCGCGAAGTCCGCCGCCTGTTAATTGGCACCTATGAAATACGTTACGAAATAGGCAATAACACTATTTAC
CTGCTGCGCATTTGGCATACACGGGAAGCGCGATAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10028.44 Da
• Isoelectric Point: 4.6533

>AT22946 WP_012489281.1 NC_010995:4451890-4452159 [Cellvibrio japonicus Ueda107]
MATADTKVITAHIPLPMAEKIDVLAARLERSRGWIIKQALATWIDQEEERNRLTREALDDVDQGRVIDHLSVTAWAESLS
TDKPLPIPE

Nucleotide

• Length: 270 bp

>AT22946 NC_010995:4451890-4452159 [Cellvibrio japonicus Ueda107]
ATGGCTACTGCTGATACTAAAGTGATAACCGCCCATATCCCGCTACCCATGGCCGAGAAAATTGATGTGCTGGCGGCGCG
CCTTGAACGCTCGCGCGGGTGGATCATCAAACAGGCACTAGCGACCTGGATTGACCAGGAAGAGGAGCGCAACCGCCTGA
CCCGTGAAGCGCTCGATGATGTTGACCAGGGGCGGGTCATTGATCACTTATCTGTCACTGCCTGGGCGGAAAGCTTAAGT
ACGGATAAGCCGCTACCGATACCTGAATAA

Structures

Toxin

• AlphaFold DB: B3PHW7

Antitoxin

• AlphaFold DB: B3PHW6