Detailed information of TA system TA022942

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 44404..45524
• Replicon: chromosome
• Accession: NC_010995
• Organism: Cellvibrio japonicus Ueda107

Toxin (Protein)

• Gene name: -
• Uniprot ID: B3PEP2
• Locus tag: CJA_RS00105
• Protein ID: WP_012485705.1
• Coordinates: 44404..45153 (-)
• Length: 250 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: B3PEP3
• Locus tag: CJA_RS00110
• Protein ID: WP_012485706.1
• Coordinates: 45153..45524 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CJA_RS00100	39679..44271	+	4593	WP_012485703.1	carbohydrate-binding protein	-
CJA_RS00105	44404..45153	-	750	WP_012485705.1	RES family NAD+ phosphorylase	Toxin
CJA_RS00110	45153..45524	-	372	WP_012485706.1	XRE family transcriptional regulator	Antitoxin
CJA_RS00115	45586..46047	-	462	WP_041551826.1	Lrp/AsnC family transcriptional regulator	-
CJA_RS00120	46479..48146	+	1668	WP_041550771.1	2-isopropylmalate synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (61-205)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (7-68)

Sequences

Toxin

Protein

• Length: 250 a.a.
• Molecular weight: 28150.78 Da
• Isoelectric Point: 5.6272

>T22942 WP_012485705.1 NC_010995:c45153-44404 [Cellvibrio japonicus Ueda107]
MIWQDCQGAQHIQTIAGTAWRLVESQEQIATLGYVDNLEEQALLEELLDGVKPPYPAQCDSYHYLLKTPFRYPPLQWGSR
FGRVHEPGIFYAGCNTQATLAESAYYRFVFWYSINAAPVKPSITSAHSLFCVDYASARGIRLQTLPFDQYQPQLTHPQDY
SATQQLGSDMRTSGVDAFEYTSARDPERNRCIGLFTPRALAQKKPREITQWLCELSANDVSFKQLGSKDIIRFPLADFLI
DGQLPTPAA

Nucleotide

• Length: 750 bp

>T22942 NC_010995:c45153-44404 [Cellvibrio japonicus Ueda107]
ATGATTTGGCAAGACTGCCAGGGAGCGCAGCACATCCAGACTATCGCCGGCACCGCCTGGCGCCTGGTGGAAAGCCAGGA
GCAAATCGCCACCCTGGGTTATGTGGATAACCTGGAAGAACAAGCCCTGCTGGAAGAATTACTCGACGGGGTAAAACCGC
CCTACCCGGCCCAGTGCGATAGTTATCACTACCTGCTCAAAACCCCTTTTCGCTATCCGCCCCTGCAATGGGGCTCGCGT
TTCGGGCGCGTCCATGAGCCGGGTATTTTCTACGCCGGCTGCAACACACAAGCAACGCTGGCTGAATCGGCCTATTACCG
TTTCGTATTTTGGTATTCCATAAACGCAGCACCGGTGAAGCCCAGCATCACCAGTGCACACAGTTTATTTTGTGTGGATT
ACGCGAGTGCGCGCGGCATTCGACTGCAAACCCTGCCGTTCGATCAATACCAGCCACAACTCACCCACCCGCAGGATTAT
TCCGCCACCCAACAATTGGGTAGTGATATGCGCACATCGGGGGTAGACGCATTTGAATACACATCCGCACGCGATCCCGA
GCGCAACAGGTGTATTGGGTTGTTCACACCAAGGGCACTGGCACAAAAGAAACCCAGGGAAATAACCCAATGGTTATGCG
AGTTAAGTGCCAATGATGTTTCTTTCAAGCAACTGGGCAGCAAGGACATTATCCGCTTTCCCCTGGCTGATTTTTTGATA
GATGGCCAACTGCCTACACCTGCTGCCTGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13225.46 Da
• Isoelectric Point: 10.7636

>AT22942 WP_012485706.1 NC_010995:c45524-45153 [Cellvibrio japonicus Ueda107]
MSALTQATPEPATVLAKAVLNAADQLGLKQAELGAVLGMHRTAISRLKQNLNLDPGSKQGELALLLIRIARALFALTGGD
KDWIRHFMHNPNQVTGGIPARQIETIQGLIQVLQFVDALRGKV

Nucleotide

• Length: 372 bp

>AT22942 NC_010995:c45524-45153 [Cellvibrio japonicus Ueda107]
ATGTCTGCACTTACCCAAGCAACGCCCGAACCAGCGACTGTACTTGCCAAAGCCGTGTTAAACGCAGCCGACCAGCTCGG
GTTAAAACAAGCCGAACTGGGTGCAGTATTGGGGATGCACCGCACGGCCATCAGTCGACTCAAGCAAAACCTCAACCTGG
ACCCCGGCTCCAAGCAGGGCGAACTGGCGCTGCTGCTGATTCGCATTGCCCGCGCGCTTTTTGCCCTTACCGGCGGCGAT
AAAGACTGGATCAGACACTTTATGCACAACCCCAACCAGGTCACCGGCGGCATTCCCGCACGCCAGATAGAAACGATTCA
GGGGTTGATCCAGGTGCTGCAATTCGTGGATGCACTGCGAGGCAAGGTGTAA

Structures

Toxin

• AlphaFold DB: B3PEP2

Antitoxin

• AlphaFold DB: B3PEP3