Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 927011..927729 Replicon chromosome
Accession NC_010994
Organism Rhizobium etli CIAT 652

Toxin (Protein)


Gene name vapC Uniprot ID B3PRC0
Locus tag RHECIAT_RS04525 Protein ID WP_012482827.1
Coordinates 927011..927469 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID B3PRC1
Locus tag RHECIAT_RS04530 Protein ID WP_012482828.1
Coordinates 927466..927729 (-) Length 88 a.a.

Genomic Context

RHECIAT_RS04515RHECIAT_RS04520RHECIAT_RS04535RHECIAT_RS04540RHECIAT_RS04505RHECIAT_RS04510RHECIAT_RS04525RHECIAT_RS04530RHECIAT_RS04545
Location: 925138..925986 (849 bp)
Type: Others
Protein ID: WP_012482825.1
Location: 926001..926984 (984 bp)
Type: Others
Protein ID: WP_012482826.1
Location: 928081..930987 (2907 bp)
Type: Others
Protein ID: WP_012482829.1
Location: 931119..931748 (630 bp)
Type: Others
Protein ID: WP_012482830.1
Location: 922799..924436 (1638 bp)
Type: Others
Protein ID: WP_012482824.1
Location: 924507..924803 (297 bp)
Type: Others
Protein ID: WP_004675403.1
Location: 927011..927469 (459 bp)
Type: Toxin
Protein ID: WP_012482827.1
Location: 927466..927729 (264 bp)
Type: Antitoxin
Protein ID: WP_012482828.1
Location: 932020..932457 (438 bp)
Type: Others
Protein ID: WP_012482831.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RHECIAT_RS04505922799..924436-1638WP_012482824.1chaperonin GroEL-
RHECIAT_RS04510924507..924803-297WP_004675403.1co-chaperone GroES-
RHECIAT_RS04515925138..925986+849WP_012482825.1TIGR01459 family HAD-type hydrolase-
RHECIAT_RS04520926001..926984+984WP_012482826.1bifunctional riboflavin kinase/FAD synthetase-
RHECIAT_RS04525927011..927469-459WP_012482827.1type II toxin-antitoxin system VapC family toxinToxin
RHECIAT_RS04530927466..927729-264WP_012482828.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
RHECIAT_RS04535928081..930987+2907WP_012482829.1isoleucine--tRNA ligase-
RHECIAT_RS04540931119..931748+630WP_012482830.1hypothetical protein-
RHECIAT_RS04545932020..932457-438WP_012482831.1nucleoside deaminase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-127)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-58)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17015.19 Da        Isoelectric Point: 6.8817

>T22939 WP_012482827.1 NC_010994:c927469-927011 [Rhizobium etli CIAT 652]
VIGWLLDTNVIAALINPNGAPSVKSWAAAQDENQMFISVLTLAEYDKGIENLPEDDRNRYRYIAARDALEERFSQRTLSL
SDAAVRHWGAISGRIKLRTGHAPPVIDTMLAATAIEHNLYLVTRNAKDTRFSGAAVFDPWTHDPNQFPLSRR

Download         Length: 459 bp

>T22939 NC_010994:c927469-927011 [Rhizobium etli CIAT 652]
GTGATCGGATGGCTGCTCGACACCAACGTCATTGCGGCGCTGATCAATCCGAACGGCGCGCCCTCTGTGAAGTCCTGGGC
TGCCGCGCAGGACGAGAACCAGATGTTCATCAGCGTGCTGACCCTCGCAGAATATGACAAAGGCATCGAAAATCTGCCTG
AAGACGACCGAAACCGCTATCGTTATATAGCGGCGCGTGACGCTCTGGAGGAGCGATTCTCACAGCGTACTCTCTCGCTG
AGCGACGCGGCTGTCAGGCATTGGGGCGCTATTTCAGGGCGCATAAAATTGCGAACCGGACATGCGCCACCGGTCATCGA
CACAATGTTGGCCGCCACCGCCATTGAGCACAATCTCTATCTGGTGACGCGGAACGCAAAGGATACGCGCTTCTCCGGCG
CGGCAGTTTTCGATCCGTGGACACACGATCCGAATCAATTTCCGTTGAGCCGGAGATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10152.71 Da        Isoelectric Point: 8.5763

>AT22939 WP_012482828.1 NC_010994:c927729-927466 [Rhizobium etli CIAT 652]
MRKIVKQSWKLEDAKARFSEVVRRARSEGPQRVTVRGRDSVVIISVEELERLTKAEPKKPLVDFMESLALKELDLEREPD
YGRDVEL

Download         Length: 264 bp

>AT22939 NC_010994:c927729-927466 [Rhizobium etli CIAT 652]
ATGAGAAAAATTGTAAAGCAAAGCTGGAAGCTCGAGGACGCCAAAGCGCGCTTCAGCGAAGTAGTACGCCGTGCCCGCAG
CGAAGGGCCGCAACGCGTGACAGTGCGCGGCAGAGACAGCGTCGTCATCATCAGCGTCGAAGAACTCGAACGGTTGACGA
AGGCCGAGCCCAAAAAGCCTTTGGTCGATTTCATGGAGAGCCTCGCTCTGAAAGAGCTCGATCTCGAGCGGGAGCCCGAT
TACGGGCGGGATGTCGAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0M3GMR1

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0M3GPB5

References