Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1439785..1440329 Replicon chromosome
Accession NC_010803
Organism Chlorobium limicola DSM 245

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CLIM_RS06715 Protein ID WP_041465707.1
Coordinates 1439785..1440120 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID B3ECY3
Locus tag CLIM_RS06720 Protein ID WP_012466285.1
Coordinates 1440117..1440329 (-) Length 71 a.a.

Genomic Context

CLIM_RS06660CLIM_RS12725CLIM_RS06670CLIM_RS06675CLIM_RS06695CLIM_RS06700CLIM_RS06705CLIM_RS06710CLIM_RS06725CLIM_RS06730CLIM_RS06680CLIM_RS06685CLIM_RS06715CLIM_RS06720CLIM_RS06735CLIM_RS12730
Location: 1435495..1435704 (210 bp)
Type: Others
Protein ID: WP_081429881.1
Location: 1435745..1436098 (354 bp)
Type: Others
Protein ID: WP_150081611.1
Location: 1436612..1436920 (309 bp)
Type: Others
Protein ID: WP_012466275.1
Location: 1436958..1437368 (411 bp)
Type: Others
Protein ID: WP_012466276.1
Location: 1438462..1438731 (270 bp)
Type: Others
Protein ID: WP_012466280.1
Location: 1438735..1438977 (243 bp)
Type: Others
Protein ID: WP_012466281.1
Location: 1439081..1439350 (270 bp)
Type: Others
Protein ID: WP_041465706.1
Location: 1439347..1439646 (300 bp)
Type: Others
Protein ID: WP_012466283.1
Location: 1440927..1441169 (243 bp)
Type: Others
Protein ID: WP_012466286.1
Location: 1441154..1441492 (339 bp)
Type: Others
Protein ID: WP_012466287.1
Location: 1437546..1437806 (261 bp)
Type: Others
Protein ID: WP_012466277.1
Location: 1437790..1438014 (225 bp)
Type: Others
Protein ID: WP_041465944.1
Location: 1439785..1440120 (336 bp)
Type: Toxin
Protein ID: WP_041465707.1
Location: 1440117..1440329 (213 bp)
Type: Antitoxin
Protein ID: WP_012466285.1
Location: 1441537..1441785 (249 bp)
Type: Others
Protein ID: WP_012466288.1
Location: 1441999..1444902 (2904 bp)
Type: Others
Protein ID: WP_012466289.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CLIM_RS066601435495..1435704+210WP_081429881.1type II toxin-antitoxin system PemK/MazF family toxin-
CLIM_RS127251435745..1436098+354WP_150081611.1GNAT family N-acetyltransferase-
CLIM_RS066701436612..1436920+309WP_012466275.1type II toxin-antitoxin system MqsR family toxin-
CLIM_RS066751436958..1437368+411WP_012466276.1type II toxin-antitoxin system MqsA family antitoxin-
CLIM_RS066801437546..1437806-261WP_012466277.1type II toxin-antitoxin system RelE/ParE family toxin-
CLIM_RS066851437790..1438014-225WP_041465944.1ribbon-helix-helix protein, CopG family-
CLIM_RS066951438462..1438731+270WP_012466280.1DUF4160 domain-containing protein-
CLIM_RS067001438735..1438977+243WP_012466281.1DUF2442 domain-containing protein-
CLIM_RS067051439081..1439350+270WP_041465706.1hypothetical protein-
CLIM_RS067101439347..1439646+300WP_012466283.1type II toxin-antitoxin system RelE/ParE family toxin-
CLIM_RS067151439785..1440120-336WP_041465707.1type II toxin-antitoxin system PemK/MazF family toxinToxin
CLIM_RS067201440117..1440329-213WP_012466285.1antitoxin MazE family proteinAntitoxin
CLIM_RS067251440927..1441169+243WP_012466286.1ribbon-helix-helix domain-containing protein-
CLIM_RS067301441154..1441492+339WP_012466287.1type II toxin-antitoxin system PemK/MazF family toxin-
CLIM_RS067351441537..1441785-249WP_012466288.1hypothetical protein-
CLIM_RS127301441999..1444902-2904WP_012466289.1DEAD/DEAH box helicase family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1423740..147151747777


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-105)

Antitoxin

Antitoxin MazE-like

(6-68)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12121.13 Da        Isoelectric Point: 9.6920

>T22904 WP_041465707.1 NC_010803:c1440120-1439785 [Chlorobium limicola DSM 245]
MKRGSVVTIALQGDYGKPRPALVVQSDYFSGHPSMTVLPITSELRQTPLFRIDVEPESGNGLRKRSQIMVDKIQTVPAEK
IVKAIGILDEATMMEVNRALALWLGFAGNPG

Download         Length: 336 bp

>T22904 NC_010803:c1440120-1439785 [Chlorobium limicola DSM 245]
ATGAAGCGCGGGTCTGTAGTGACGATCGCATTGCAGGGTGATTATGGTAAACCTCGGCCCGCATTGGTTGTGCAGTCTGA
TTATTTCTCAGGACATCCATCGATGACTGTTTTACCGATTACCAGTGAGTTGCGTCAGACGCCGTTATTCAGAATCGATG
TCGAGCCTGAATCCGGTAATGGATTGCGTAAGCGTTCCCAGATCATGGTCGATAAAATACAGACTGTTCCGGCAGAAAAA
ATCGTCAAAGCCATCGGTATTCTTGACGAAGCAACCATGATGGAAGTCAACAGGGCGCTTGCGCTTTGGTTAGGATTTGC
CGGTAATCCAGGGTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8417.58 Da        Isoelectric Point: 9.1636

>AT22904 WP_012466285.1 NC_010803:c1440329-1440117 [Chlorobium limicola DSM 245]
MKVVTERVKRYRDRLRERGLRPVQIWVADTRRPGFEQECRRQSALLKSDALEKEVLEFLEQASDREGWEA

Download         Length: 213 bp

>AT22904 NC_010803:c1440329-1440117 [Chlorobium limicola DSM 245]
ATGAAAGTTGTTACAGAAAGGGTAAAGCGGTACAGGGACAGGCTTCGGGAGCGCGGATTGAGACCGGTGCAGATATGGGT
GGCGGATACGCGGCGTCCCGGATTCGAACAGGAGTGCCGCCGTCAATCGGCGCTGCTCAAGTCGGATGCTCTTGAAAAAG
AGGTTCTTGAATTTCTTGAGCAGGCCTCAGATCGGGAAGGTTGGGAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBB3ECY3

References