Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | chpSB/PRK09812-ChpS |
Location | 516392..516987 | Replicon | chromosome |
Accession | NC_010801 | ||
Organism | Burkholderia multivorans ATCC 17616 |
Toxin (Protein)
Gene name | chpB | Uniprot ID | A0A2A4C4A8 |
Locus tag | BMULJ_RS29090 | Protein ID | WP_012218081.1 |
Coordinates | 516637..516987 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | chpS | Uniprot ID | A0A2A4C1X6 |
Locus tag | BMULJ_RS29085 | Protein ID | WP_012218082.1 |
Coordinates | 516392..516643 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BMULJ_RS29055 | 512341..512847 | - | 507 | WP_012218086.1 | arsenate reductase (azurin) small subunit | - |
BMULJ_RS29065 | 513740..513934 | + | 195 | WP_012464904.1 | hypothetical protein | - |
BMULJ_RS29070 | 514107..514898 | - | 792 | WP_012218085.1 | SOS response-associated peptidase family protein | - |
BMULJ_RS29075 | 515029..515355 | - | 327 | WP_012464905.1 | H-NS histone family protein | - |
BMULJ_RS29080 | 515520..516200 | + | 681 | WP_012218083.1 | site-specific integrase | - |
BMULJ_RS29085 | 516392..516643 | + | 252 | WP_012218082.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
BMULJ_RS29090 | 516637..516987 | + | 351 | WP_012218081.1 | type II toxin-antitoxin system ChpB family toxin | Toxin |
BMULJ_RS29095 | 516998..517510 | + | 513 | WP_012218080.1 | hypothetical protein | - |
BMULJ_RS29100 | 517573..517758 | + | 186 | WP_038442441.1 | hypothetical protein | - |
BMULJ_RS34845 | 517755..517916 | - | 162 | WP_155295622.1 | hypothetical protein | - |
BMULJ_RS34850 | 518001..518333 | + | 333 | WP_096508413.1 | hypothetical protein | - |
BMULJ_RS34855 | 518357..518926 | + | 570 | WP_012218078.1 | hypothetical protein | - |
BMULJ_RS33990 | 519140..520084 | + | 945 | WP_012218077.1 | hypothetical protein | - |
BMULJ_RS29105 | 520140..520394 | + | 255 | WP_038442290.1 | hypothetical protein | - |
BMULJ_RS34860 | 520404..520847 | + | 444 | WP_143331194.1 | hypothetical protein | - |
BMULJ_RS29110 | 520866..521225 | + | 360 | WP_012218076.1 | hypothetical protein | - |
BMULJ_RS29115 | 521243..521452 | + | 210 | WP_038442273.1 | hypothetical protein | - |
BMULJ_RS33995 | 521473..521862 | + | 390 | WP_080512399.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12420.35 Da Isoelectric Point: 8.9716
>T22900 WP_012218081.1 NC_010801:516637-516987 [Burkholderia multivorans ATCC 17616]
MVKRVKFDRGDIVRVSLNRTIGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLEARGARTIERAPAEVVEDALARLQSIIE
MVKRVKFDRGDIVRVSLNRTIGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLEARGARTIERAPAEVVEDALARLQSIIE
Download Length: 351 bp
>T22900 NC_010801:516637-516987 [Burkholderia multivorans ATCC 17616]
ATGGTAAAGCGGGTCAAGTTCGATCGGGGCGACATCGTGCGCGTTAGCCTGAACCGGACCATCGGGCGCGAGCAGCAGGG
CGATTTCCGTCCCGCGCTTGTGCTGTCTCCCGCCGCATTCAATGCCTTGGGGGTGGCGCTCGTCGCGCCGATCACGCAGG
GCGGGGAGTTTGCGCGCTTCGCAGGATTCGCCGTGCCGCTCTCTGGCTCGGGCACCGAGACGCAGGGCGTGGCCTTGGTG
AACATGGTCCGGATGCTCGATCTGGAGGCGCGTGGCGCACGGACGATCGAGCGGGCTCCGGCCGAGGTGGTCGAAGATGC
GCTGGCTCGGCTGCAATCGATAATCGAGTAG
ATGGTAAAGCGGGTCAAGTTCGATCGGGGCGACATCGTGCGCGTTAGCCTGAACCGGACCATCGGGCGCGAGCAGCAGGG
CGATTTCCGTCCCGCGCTTGTGCTGTCTCCCGCCGCATTCAATGCCTTGGGGGTGGCGCTCGTCGCGCCGATCACGCAGG
GCGGGGAGTTTGCGCGCTTCGCAGGATTCGCCGTGCCGCTCTCTGGCTCGGGCACCGAGACGCAGGGCGTGGCCTTGGTG
AACATGGTCCGGATGCTCGATCTGGAGGCGCGTGGCGCACGGACGATCGAGCGGGCTCCGGCCGAGGTGGTCGAAGATGC
GCTGGCTCGGCTGCAATCGATAATCGAGTAG
Antitoxin
Download Length: 84 a.a. Molecular weight: 8997.39 Da Isoelectric Point: 6.9770
>AT22900 WP_012218082.1 NC_010801:516392-516643 [Burkholderia multivorans ATCC 17616]
MELKIQKWGNSAAVRLPAVLLEQMHASVGGSLNADVRPDGVLLTPARRKYALDELVAQCDAKAPFPADMAAWGEVRPVGR
EGW
MELKIQKWGNSAAVRLPAVLLEQMHASVGGSLNADVRPDGVLLTPARRKYALDELVAQCDAKAPFPADMAAWGEVRPVGR
EGW
Download Length: 252 bp
>AT22900 NC_010801:516392-516643 [Burkholderia multivorans ATCC 17616]
ATGGAACTAAAAATTCAGAAATGGGGCAACAGTGCGGCGGTGCGACTCCCCGCCGTGTTGCTCGAGCAGATGCACGCCTC
GGTCGGCGGCTCGCTGAACGCCGACGTGCGTCCGGACGGCGTATTGCTGACCCCCGCGCGCCGCAAGTATGCGCTGGACG
AACTGGTCGCTCAGTGTGATGCGAAAGCGCCTTTCCCGGCGGACATGGCTGCATGGGGTGAGGTCAGGCCGGTAGGGCGT
GAAGGATGGTAA
ATGGAACTAAAAATTCAGAAATGGGGCAACAGTGCGGCGGTGCGACTCCCCGCCGTGTTGCTCGAGCAGATGCACGCCTC
GGTCGGCGGCTCGCTGAACGCCGACGTGCGTCCGGACGGCGTATTGCTGACCCCCGCGCGCCGCAAGTATGCGCTGGACG
AACTGGTCGCTCAGTGTGATGCGAAAGCGCCTTTCCCGGCGGACATGGCTGCATGGGGTGAGGTCAGGCCGGTAGGGCGT
GAAGGATGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2A4C4A8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2A4C1X6 |