Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 5068109..5068759 Replicon chromosome
Accession NC_010725
Organism Methylobacterium populi BJ001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPOP_RS23430 Protein ID WP_041372166.1
Coordinates 5068505..5068759 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPOP_RS23425 Protein ID WP_012456436.1
Coordinates 5068109..5068483 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPOP_RS23405 5063874..5064404 - 531 WP_012456432.1 GNAT family N-acetyltransferase -
MPOP_RS23410 5064582..5065013 + 432 WP_012456433.1 DUF983 domain-containing protein -
MPOP_RS23415 5065089..5066828 - 1740 WP_012456434.1 L-lactate permease -
MPOP_RS23420 5067133..5068056 + 924 WP_012456435.1 manganese catalase family protein -
MPOP_RS23425 5068109..5068483 - 375 WP_012456436.1 helix-turn-helix transcriptional regulator Antitoxin
MPOP_RS23430 5068505..5068759 - 255 WP_041372166.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MPOP_RS23435 5068849..5069745 - 897 WP_012456438.1 squalene/phytoene synthase family protein -
MPOP_RS23440 5069775..5070173 - 399 WP_012456439.1 membrane protein -
MPOP_RS23445 5070292..5071236 - 945 WP_012456440.1 protein translocase subunit SecF -
MPOP_RS23450 5071342..5072943 - 1602 WP_012456441.1 protein translocase subunit SecD -
MPOP_RS23455 5073008..5073340 - 333 WP_012456442.1 preprotein translocase subunit YajC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(71-122)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9261.88 Da        Isoelectric Point: 10.6598

>T22895 WP_041372166.1 NC_010725:c5068759-5068505 [Methylorubrum populi BJ001]
MAEVVYSKAALRALIRLPTDVSRKIRLKIEQYAAKPGSLANNVKALRGEPGVLRLRVGDWRVLFTEEGTVVAVIKIAPRG
DAYD

Download         Length: 255 bp

>T22895 NC_010725:c5068759-5068505 [Methylorubrum populi BJ001]
ATGGCTGAAGTCGTCTACAGCAAAGCTGCCTTGAGGGCTTTGATCCGACTTCCTACGGATGTGTCTCGGAAGATCCGCCT
CAAGATCGAGCAATACGCGGCCAAACCCGGGTCGCTCGCCAACAACGTGAAAGCGCTTCGAGGCGAGCCCGGCGTCCTGC
GTCTGCGGGTCGGAGATTGGCGCGTGCTCTTCACCGAGGAAGGCACCGTGGTTGCCGTCATCAAGATCGCACCACGGGGT
GACGCTTACGACTGA

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 13171.88 Da        Isoelectric Point: 4.6361

>AT22895 WP_012456436.1 NC_010725:c5068483-5068109 [Methylorubrum populi BJ001]
MNTRIIITPGGERLVLVPEADFEALVAAAEDNADRTAVAEFRRKLAAGEEELIPASVVERLVSGENRVRVWREHRGLTGA
ALAKQAGLAQAYLSQIETGAREGTVETYSKLAAALGVSLDDLAG

Download         Length: 375 bp

>AT22895 NC_010725:c5068483-5068109 [Methylorubrum populi BJ001]
ATGAACACGCGGATCATCATCACCCCCGGCGGCGAGCGTCTCGTGCTGGTGCCCGAGGCAGACTTCGAAGCGCTGGTGGC
AGCGGCCGAAGACAACGCCGACCGCACCGCCGTGGCGGAGTTCCGTCGCAAGCTCGCCGCGGGCGAGGAGGAGCTGATCC
CGGCTTCCGTCGTAGAGCGTCTCGTCTCCGGCGAGAATCGTGTCCGTGTCTGGCGCGAGCACCGGGGCCTGACGGGAGCC
GCGCTGGCGAAGCAGGCAGGTCTCGCACAGGCTTACCTGTCGCAGATCGAGACCGGGGCACGGGAAGGCACGGTGGAAAC
CTACAGCAAGCTTGCCGCGGCCCTGGGCGTTTCCCTGGACGATCTCGCCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References