22884

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4951346..4951696 Replicon chromosome
Accession NC_010717
Organism Xanthomonas oryzae pv. oryzae PXO99A

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag PXO_RS22615 Protein ID WP_011257368.1
Coordinates 4951346..4951480 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag PXO_RS22620 Protein ID WP_011407410.1
Coordinates 4951544..4951696 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXO_RS22600 4948360..4949382 - 1023 WP_075240574.1 MBL fold metallo-hydrolase -
PXO_RS22605 4949435..4950724 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
PXO_RS22610 4950893..4951102 - 210 WP_011407411.1 CsbD family protein -
PXO_RS22615 4951346..4951480 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
PXO_RS22620 4951544..4951696 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
PXO_RS22625 4951804..4952727 - 924 WP_011407409.1 arginase -
PXO_RS22630 4953049..4953723 + 675 WP_011257366.1 hypothetical protein -
PXO_RS22635 4953720..4953959 + 240 WP_011257365.1 hypothetical protein -
PXO_RS22640 4953966..4954262 + 297 WP_012446308.1 hypothetical protein -
PXO_RS22645 4954742..4955425 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T22884 WP_011257368.1 NC_010717:c4951480-4951346 [Xanthomonas oryzae pv. oryzae PXO99A]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T22884 NC_010717:c4951480-4951346 [Xanthomonas oryzae pv. oryzae PXO99A]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT22884 WP_011407410.1 NC_010717:c4951696-4951544 [Xanthomonas oryzae pv. oryzae PXO99A]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT22884 NC_010717:c4951696-4951544 [Xanthomonas oryzae pv. oryzae PXO99A]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References