Detailed information of TA system TA022882

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1973248..1973804
• Replicon: chromosome
• Accession: NC_010717
• Organism: Xanthomonas oryzae pv. oryzae PXO99A

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: PXO_RS08965
• Protein ID: WP_041182647.1
• Coordinates: 1973514..1973804 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: PXO_RS08960
• Protein ID: WP_011408759.1
• Coordinates: 1973248..1973526 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PXO_RS25840	1968365..1968970	-	606	Protein_1761	DNA-3-methyladenine glycosylase	-
PXO_RS08950	1969072..1970037	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
PXO_RS08955	1970618..1971802	+	1185	WP_011408397.1	IS256 family transposase	-
PXO_RS25845	1972563..1972763	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
PXO_RS30005	1972708..1973052	+	345	WP_198912817.1	hypothetical protein	-
PXO_RS30010	1972964..1973167	+	204	WP_198912807.1	hypothetical protein	-
PXO_RS08960	1973248..1973526	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
PXO_RS08965	1973514..1973804	+	291	WP_041182647.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PXO_RS25855	1973881..1974135	+	255	WP_198912806.1	hypothetical protein	-
PXO_RS08975	1974406..1974585	+	180	WP_015463309.1	hypothetical protein	-
PXO_RS30015	1974857..1975018	+	162	WP_200898177.1	hypothetical protein	-
PXO_RS25865	1975087..1975885	+	799	WP_094187731.1	IS5 family transposase	-
PXO_RS08995	1976301..1976702	-	402	WP_011259345.1	H-NS histone family protein	-
PXO_RS29795	1976924..1977100	+	177	Protein_1774	DUF3606 domain-containing protein	-
PXO_RS29585	1977116..1977322	+	207	Protein_1775	hypothetical protein	-
PXO_RS09005	1977382..1977698	+	317	Protein_1776	ATP-dependent DNA ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1969072..1975885	6813

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10929.51 Da
• Isoelectric Point: 9.5554

>T22882 WP_041182647.1 NC_010717:1973514-1973804 [Xanthomonas oryzae pv. oryzae PXO99A]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILALRHQKEAGY

Nucleotide

• Length: 291 bp

>T22882 NC_010717:1973514-1973804 [Xanthomonas oryzae pv. oryzae PXO99A]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCCTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT22882 WP_011408759.1 NC_010717:1973248-1973526 [Xanthomonas oryzae pv. oryzae PXO99A]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT22882 NC_010717:1973248-1973526 [Xanthomonas oryzae pv. oryzae PXO99A]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2