Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4645710..4646073 Replicon chromosome
Accession NC_010688
Organism Xanthomonas campestris pv. campestris str. B100

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XCCB100_RS19990 Protein ID WP_011270059.1
Coordinates 4645710..4645844 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XCCB100_RS19995 Protein ID WP_011038999.1
Coordinates 4645921..4646073 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCCB100_RS19970 4640974..4642626 - 1653 WP_043890286.1 M28 family peptidase -
XCCB100_RS19975 4642791..4643735 - 945 WP_043890287.1 MBL fold metallo-hydrolase -
XCCB100_RS19980 4643819..4645108 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
XCCB100_RS19985 4645268..4645477 - 210 WP_011038998.1 CsbD family protein -
XCCB100_RS19990 4645710..4645844 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XCCB100_RS19995 4645921..4646073 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XCCB100_RS20000 4646184..4647107 - 924 WP_012439504.1 arginase -
XCCB100_RS20005 4647421..4647882 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
XCCB100_RS20010 4647965..4648324 + 360 WP_011039002.1 hypothetical protein -
XCCB100_RS20015 4648427..4649344 + 918 WP_012439506.1 hypothetical protein -
XCCB100_RS20020 4649341..4649883 + 543 WP_012439507.1 GTPase -
XCCB100_RS20025 4650218..4650901 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T22872 WP_011270059.1 NC_010688:c4645844-4645710 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T22872 NC_010688:c4645844-4645710 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT22872 WP_011038999.1 NC_010688:c4646073-4645921 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT22872 NC_010688:c4646073-4645921 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References