Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 4248946..4249535 | Replicon | chromosome |
Accession | NC_010681 | ||
Organism | Burkholderia phytofirmans PsJN |
Toxin (Protein)
Gene name | hicA | Uniprot ID | B2T7A5 |
Locus tag | BPHYT_RS18915 | Protein ID | WP_012434712.1 |
Coordinates | 4248946..4249128 (+) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | B2T7A6 |
Locus tag | BPHYT_RS18920 | Protein ID | WP_012434713.1 |
Coordinates | 4249125..4249535 (+) | Length | 137 a.a. |
Genomic Context
Location: 4246027..4247541 (1515 bp)
Type: Others
Protein ID: WP_012434709.1
Type: Others
Protein ID: WP_012434709.1
Location: 4247743..4248096 (354 bp)
Type: Others
Protein ID: WP_012434710.1
Type: Others
Protein ID: WP_012434710.1
Location: 4248191..4248637 (447 bp)
Type: Others
Protein ID: WP_012434711.1
Type: Others
Protein ID: WP_012434711.1
Location: 4248946..4249128 (183 bp)
Type: Toxin
Protein ID: WP_012434712.1
Type: Toxin
Protein ID: WP_012434712.1
Location: 4249125..4249535 (411 bp)
Type: Antitoxin
Protein ID: WP_012434713.1
Type: Antitoxin
Protein ID: WP_012434713.1
Location: 4244064..4244786 (723 bp)
Type: Others
Protein ID: WP_012434706.1
Type: Others
Protein ID: WP_012434706.1
Location: 4244797..4245222 (426 bp)
Type: Others
Protein ID: WP_012434707.1
Type: Others
Protein ID: WP_012434707.1
Location: 4245315..4245809 (495 bp)
Type: Others
Protein ID: WP_012434708.1
Type: Others
Protein ID: WP_012434708.1
Location: 4249596..4250330 (735 bp)
Type: Others
Protein ID: WP_012434714.1
Type: Others
Protein ID: WP_012434714.1
Location: 4250359..4251228 (870 bp)
Type: Others
Protein ID: WP_041758634.1
Type: Others
Protein ID: WP_041758634.1
Location: 4251221..4253146 (1926 bp)
Type: Others
Protein ID: WP_041758636.1
Type: Others
Protein ID: WP_041758636.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BPHYT_RS18885 | 4244064..4244786 | - | 723 | WP_012434706.1 | flagellar hook assembly protein FlgD | - |
BPHYT_RS18890 | 4244797..4245222 | - | 426 | WP_012434707.1 | flagellar basal body rod protein FlgC | - |
BPHYT_RS18895 | 4245315..4245809 | - | 495 | WP_012434708.1 | flagellar basal body rod protein FlgB | - |
BPHYT_RS18900 | 4246027..4247541 | + | 1515 | WP_012434709.1 | flagellar basal body P-ring formation protein FlgA | - |
BPHYT_RS18905 | 4247743..4248096 | + | 354 | WP_012434710.1 | flagellar biosynthesis anti-sigma factor FlgM | - |
BPHYT_RS18910 | 4248191..4248637 | + | 447 | WP_012434711.1 | flagellar protein FlgN | - |
BPHYT_RS18915 | 4248946..4249128 | + | 183 | WP_012434712.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
BPHYT_RS18920 | 4249125..4249535 | + | 411 | WP_012434713.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
BPHYT_RS18925 | 4249596..4250330 | - | 735 | WP_012434714.1 | RNA polymerase sigma factor FliA | - |
BPHYT_RS18930 | 4250359..4251228 | - | 870 | WP_041758634.1 | AAA family ATPase | - |
BPHYT_RS18935 | 4251221..4253146 | - | 1926 | WP_041758636.1 | flagellar biosynthesis protein FlhF | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6629.78 Da Isoelectric Point: 11.3940
>T22870 WP_012434712.1 NC_010681:4248946-4249128 [Paraburkholderia phytofirmans PsJN]
MKSAEVVKLIQTAGWQVVRITGSHHHFRHAERTGLVTIPHPKKDLPPGTLNSILKQAGLK
MKSAEVVKLIQTAGWQVVRITGSHHHFRHAERTGLVTIPHPKKDLPPGTLNSILKQAGLK
Download Length: 183 bp
>T22870 NC_010681:4248946-4249128 [Paraburkholderia phytofirmans PsJN]
ATGAAAAGTGCCGAGGTCGTGAAACTCATTCAAACGGCGGGTTGGCAGGTGGTCCGCATAACGGGCAGCCACCATCATTT
TCGTCACGCGGAAAGAACCGGTCTCGTGACCATCCCGCATCCGAAGAAAGATCTTCCGCCCGGCACATTGAACAGCATCC
TGAAACAGGCGGGCCTGAAATGA
ATGAAAAGTGCCGAGGTCGTGAAACTCATTCAAACGGCGGGTTGGCAGGTGGTCCGCATAACGGGCAGCCACCATCATTT
TCGTCACGCGGAAAGAACCGGTCTCGTGACCATCCCGCATCCGAAGAAAGATCTTCCGCCCGGCACATTGAACAGCATCC
TGAAACAGGCGGGCCTGAAATGA
Antitoxin
Download Length: 137 a.a. Molecular weight: 14779.81 Da Isoelectric Point: 4.6327
>AT22870 WP_012434713.1 NC_010681:4249125-4249535 [Paraburkholderia phytofirmans PsJN]
MKNLTFPIAIEPGSADHAFGVIVPDIPGCYAAGDTLEEAYANAKEAIEAHLDVLLDEGLPIPARRTLQEHRRNPDYADFT
WGLVATRNIPALKKAVRINISLPEALVQEIDAYAQARGMSRSAFLALAAEHEMAEA
MKNLTFPIAIEPGSADHAFGVIVPDIPGCYAAGDTLEEAYANAKEAIEAHLDVLLDEGLPIPARRTLQEHRRNPDYADFT
WGLVATRNIPALKKAVRINISLPEALVQEIDAYAQARGMSRSAFLALAAEHEMAEA
Download Length: 411 bp
>AT22870 NC_010681:4249125-4249535 [Paraburkholderia phytofirmans PsJN]
ATGAAGAACCTGACTTTCCCTATCGCGATCGAGCCGGGGAGCGCGGATCACGCGTTCGGCGTCATCGTGCCGGACATTCC
GGGCTGTTATGCGGCGGGCGATACGCTGGAAGAAGCCTACGCGAATGCCAAGGAGGCTATCGAGGCCCACCTTGACGTCC
TGCTCGACGAGGGCTTGCCGATTCCCGCGCGGCGTACGCTGCAAGAGCACCGGCGCAATCCCGACTATGCGGATTTCACG
TGGGGGCTTGTCGCCACCCGGAATATTCCCGCCTTGAAGAAGGCGGTACGTATCAATATCTCGCTGCCCGAAGCGCTGGT
CCAGGAGATCGACGCTTATGCCCAGGCGCGCGGCATGTCGCGCTCGGCCTTTCTGGCGCTGGCCGCGGAACATGAAATGG
CCGAGGCATGA
ATGAAGAACCTGACTTTCCCTATCGCGATCGAGCCGGGGAGCGCGGATCACGCGTTCGGCGTCATCGTGCCGGACATTCC
GGGCTGTTATGCGGCGGGCGATACGCTGGAAGAAGCCTACGCGAATGCCAAGGAGGCTATCGAGGCCCACCTTGACGTCC
TGCTCGACGAGGGCTTGCCGATTCCCGCGCGGCGTACGCTGCAAGAGCACCGGCGCAATCCCGACTATGCGGATTTCACG
TGGGGGCTTGTCGCCACCCGGAATATTCCCGCCTTGAAGAAGGCGGTACGTATCAATATCTCGCTGCCCGAAGCGCTGGT
CCAGGAGATCGACGCTTATGCCCAGGCGCGCGGCATGTCGCGCTCGGCCTTTCTGGCGCTGGCCGCGGAACATGAAATGG
CCGAGGCATGA