Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4320725..4320870 Replicon chromosome
Accession NZ_CP089771
Organism Klebsiella pneumoniae strain HKE12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4320732..4320834 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4320725..4320870 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVO50_RS20990 4316258..4317691 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LVO50_RS20995 4317807..4318046 + 240 WP_002911393.1 YebV family protein -
LVO50_RS21000 4318144..4318335 + 192 WP_002911395.1 YebW family protein -
LVO50_RS21005 4318332..4318985 - 654 WP_004189273.1 protein-serine/threonine phosphatase -
LVO50_RS21010 4319142..4320110 + 969 WP_004151446.1 VirK/YbjX family protein -
LVO50_RS21015 4320215..4320358 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4320725..4320870 + 146 - - Antitoxin
- 4320732..4320834 - 103 - - Toxin
LVO50_RS21020 4320993..4321331 - 339 WP_002911404.1 YebY family protein -
LVO50_RS21025 4321348..4322217 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LVO50_RS21030 4322221..4322595 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LVO50_RS21035 4322708..4322938 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LVO50_RS21040 4323017..4323675 + 659 Protein_4120 exodeoxyribonuclease X -
LVO50_RS21045 4323679..4325739 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228650 NZ_CP089771:c4320834-4320732 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAGGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228650 NZ_CP089771:4320725-4320870 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCCTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References