Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1529426..1529571 Replicon chromosome
Accession NZ_CP089768
Organism Klebsiella pneumoniae strain HKE9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1529462..1529564 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1529426..1529571 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVO52_RS07390 1524557..1526617 + 2061 WP_277695965.1 oligopeptidase B -
LVO52_RS07395 1526621..1527280 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVO52_RS07400 1527359..1527589 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVO52_RS07405 1527702..1528076 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVO52_RS07410 1528080..1528949 + 870 WP_040224089.1 copper homeostasis membrane protein CopD -
LVO52_RS07415 1528966..1529304 + 339 WP_002911404.1 YebY family protein -
- 1529426..1529571 - 146 - - Antitoxin
- 1529462..1529564 + 103 - - Toxin
LVO52_RS07420 1529940..1530083 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVO52_RS07425 1530188..1531156 - 969 WP_004151446.1 VirK/YbjX family protein -
LVO52_RS07430 1531313..1531966 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
LVO52_RS07435 1531963..1532154 - 192 WP_002911395.1 YebW family protein -
LVO52_RS07440 1532252..1532491 - 240 WP_002911393.1 YebV family protein -
LVO52_RS07445 1532607..1534040 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228623 NZ_CP089768:1529462-1529564 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228623 NZ_CP089768:c1529571-1529426 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References