Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3715905..3716050 Replicon chromosome
Accession NZ_CP089765
Organism Klebsiella pneumoniae strain HKC2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3715941..3716043 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3715905..3716050 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVO53_RS18045 3711035..3713095 + 2061 WP_004151449.1 oligopeptidase B -
LVO53_RS18050 3713099..3713758 - 660 WP_004180433.1 exodeoxyribonuclease X -
LVO53_RS18055 3713837..3714067 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVO53_RS18060 3714180..3714554 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVO53_RS18065 3714558..3715427 + 870 WP_277709594.1 copper homeostasis membrane protein CopD -
LVO53_RS18070 3715444..3715782 + 339 WP_002911404.1 YebY family protein -
- 3715905..3716050 - 146 - - Antitoxin
- 3715941..3716043 + 103 - - Toxin
LVO53_RS18075 3716419..3716562 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVO53_RS18080 3716667..3717635 - 969 WP_004151446.1 VirK/YbjX family protein -
LVO53_RS18085 3717792..3718445 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LVO53_RS18090 3718442..3718633 - 192 WP_002911395.1 YebW family protein -
LVO53_RS18095 3718731..3718970 - 240 WP_002911393.1 YebV family protein -
LVO53_RS18100 3719086..3720519 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228608 NZ_CP089765:3715941-3716043 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228608 NZ_CP089765:c3716050-3715905 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References