Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1271465..1271610 Replicon chromosome
Accession NZ_CP089762
Organism Klebsiella pneumoniae strain HKC1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1271501..1271603 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1271465..1271610 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVO51_RS06215 (LVO51_06195) 1266595..1268655 + 2061 WP_004151449.1 oligopeptidase B -
LVO51_RS06220 (LVO51_06200) 1268659..1269318 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVO51_RS06225 (LVO51_06205) 1269397..1269627 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVO51_RS06230 (LVO51_06210) 1269740..1270114 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVO51_RS06235 (LVO51_06215) 1270118..1270987 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LVO51_RS06240 (LVO51_06220) 1271004..1271342 + 339 WP_002911404.1 YebY family protein -
- 1271465..1271610 - 146 - - Antitoxin
- 1271501..1271603 + 103 - - Toxin
LVO51_RS06245 (LVO51_06225) 1271978..1272121 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVO51_RS06250 (LVO51_06230) 1272226..1273194 - 969 WP_004151446.1 VirK/YbjX family protein -
LVO51_RS06255 (LVO51_06235) 1273351..1274004 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LVO51_RS06260 (LVO51_06240) 1274001..1274192 - 192 WP_002911395.1 YebW family protein -
LVO51_RS06265 (LVO51_06245) 1274290..1274529 - 240 WP_002911393.1 YebV family protein -
LVO51_RS06270 (LVO51_06250) 1274645..1276078 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228579 NZ_CP089762:1271501-1271603 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228579 NZ_CP089762:c1271610-1271465 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References