Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071971..2072116 Replicon chromosome
Accession NZ_CP089598
Organism Klebsiella pneumoniae strain KP29499

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2072007..2072109 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071971..2072116 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVE73_RS09915 2067101..2069161 + 2061 WP_004151449.1 oligopeptidase B -
LVE73_RS09920 2069165..2069824 - 660 WP_002911407.1 exodeoxyribonuclease X -
LVE73_RS09925 2069903..2070133 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVE73_RS09930 2070246..2070620 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVE73_RS09935 2070624..2071493 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
LVE73_RS09940 2071510..2071848 + 339 WP_002911404.1 YebY family protein -
- 2071971..2072116 - 146 - - Antitoxin
- 2072007..2072109 + 103 - - Toxin
LVE73_RS09945 2072484..2072627 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVE73_RS09950 2072732..2073700 - 969 WP_014907334.1 VirK/YbjX family protein -
LVE73_RS09955 2073857..2074510 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LVE73_RS09960 2074507..2074698 - 192 WP_002911395.1 YebW family protein -
LVE73_RS09965 2074796..2075035 - 240 WP_002911393.1 YebV family protein -
LVE73_RS09970 2075151..2076584 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228415 NZ_CP089598:2072007-2072109 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228415 NZ_CP089598:c2072116-2071971 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References