Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 78264..78894 Replicon chromosome
Accession NZ_CP089590
Organism Microbacterium sp. J1-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LRQ07_RS00375 Protein ID WP_256535482.1
Coordinates 78264..78680 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LRQ07_RS00380 Protein ID WP_226533466.1
Coordinates 78664..78894 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRQ07_RS00360 (LRQ07_00355) 74851..75705 - 855 WP_256535479.1 hypothetical protein -
LRQ07_RS00365 (LRQ07_00360) 75702..76337 - 636 WP_256535480.1 TetR/AcrR family transcriptional regulator -
LRQ07_RS00370 (LRQ07_00365) 76755..78200 - 1446 WP_256535481.1 argininosuccinate synthase -
LRQ07_RS00375 (LRQ07_00370) 78264..78680 - 417 WP_256535482.1 VapC toxin family PIN domain ribonuclease Toxin
LRQ07_RS00380 (LRQ07_00375) 78664..78894 - 231 WP_226533466.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LRQ07_RS00385 (LRQ07_00380) 78979..79464 + 486 WP_232762997.1 hypothetical protein -
LRQ07_RS00390 (LRQ07_00385) 79630..80346 + 717 WP_256535483.1 hypothetical protein -
LRQ07_RS00395 (LRQ07_00390) 80378..80785 - 408 WP_153243276.1 pyridoxamine 5'-phosphate oxidase family protein -
LRQ07_RS00400 (LRQ07_00395) 80990..81961 + 972 WP_232762995.1 alpha/beta hydrolase -
LRQ07_RS00405 (LRQ07_00400) 82094..83089 + 996 WP_256535484.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

SpoVT-AbrB domain

(2-37)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14257.36 Da        Isoelectric Point: 6.4773

>T228387 WP_256535482.1 NZ_CP089590:c78680-78264 [Microbacterium sp. J1-1]
MPISADLLLDTSAAIALVHDRNPAHERMLELTHGRVIGLAGHAAVETYSVLTRLPGAARVSPGRAQEIIDRSFPASAPLS
PTTAAAAITTFAEAGIAGGSVYDGLVGLAARDTAVPLLTCDRRALGTYAALRVEFLLA

Download         Length: 417 bp

>T228387 NZ_CP123897:3347539-3347835 [Methylomonas sp. UP202]
ATGAAGCCCAGCTATCGCATCAGGCAACTGGCGGCGGAGGATTTGGAGCATATTTGGCTTTATACGTTTCAACAATGGGG
TCCCGAGCAAGCCGACCGATACCTACGCGCACTGTTCGACCGCTTCACTTGGCTTGCGGAATACCCCAAGCTAGGCAAGG
CGCGCGACGATATAAAACCCGGTTATTTTTGCTTCCCCGAAGGCCGGCATTTAGTTTTTTACATCGCTACCAATACCGGC
ATAGAAATAATCGGCGTCCCTCATCAGAACATGGATGTCATTAATCATGTTGGATGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8283.64 Da        Isoelectric Point: 4.7420

>AT228387 WP_226533466.1 NZ_CP089590:c78894-78664 [Microbacterium sp. J1-1]
MRATMDKAGRIVIPAALRERVGLIPGPVDLLLDGNGIRIEIDAPDNLIEKDGRLIITGGPTLTVDEVRELRLADQR

Download         Length: 231 bp

>AT228387 NZ_CP123897:3347297-3347542 [Methylomonas sp. UP202]
ATGGCTAGAAATACTTCCGTCACTTTAGGCGACCACTTTGATAACTTCGTGCAGGAAAAAATACAGCAAGGCCGTTTCTT
GTCGGTTAGCGAGGCCGTCCGCGCCGGCTTGCGTAAACTGGAAGAAGAGGAACTTAAGCTACAAACATTAAGAGCCAAGC
TGCAAGCCGGCGAAGACAGCCCCTTGCAGGAGAATTTCGACCAAGAGCAATTTCTGGCCTCGATGCGAAAAAAACATAGC
CTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References