228368

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4349529..4349914 Replicon chromosome
Accession NZ_CP089584
Organism Xanthomonas translucens pv. undulosa strain MAI5034

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag LTC53_RS18930 Protein ID WP_003469322.1
Coordinates 4349529..4349663 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag LTC53_RS18935 Protein ID WP_003469323.1
Coordinates 4349762..4349914 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LTC53_RS18915 (LTC53_18915) 4345973..4346896 - 924 WP_235049144.1 MBL fold metallo-hydrolase -
LTC53_RS18920 (LTC53_18920) 4346966..4348366 - 1401 WP_235049145.1 tryptophan--tRNA ligase -
LTC53_RS18925 (LTC53_18925) 4348477..4349319 + 843 WP_235049146.1 hypothetical protein -
LTC53_RS18930 (LTC53_18930) 4349529..4349663 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
LTC53_RS18935 (LTC53_18935) 4349762..4349914 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
LTC53_RS18940 (LTC53_18940) 4350059..4350981 - 923 Protein_3740 arginase -
LTC53_RS18950 (LTC53_18950) 4351387..4352205 - 819 WP_047325438.1 SPOR domain-containing protein -
LTC53_RS18955 (LTC53_18955) 4352215..4352955 - 741 WP_047325439.1 type III pantothenate kinase -
LTC53_RS18960 (LTC53_18960) 4352952..4353971 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
LTC53_RS18965 (LTC53_18965) 4354076..4354339 + 264 WP_038238001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T228368 WP_003469322.1 NZ_CP089584:c4349663-4349529 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T228368 NZ_CP123853:2304336-2304578 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAGTTAGATTTAAAGAAGACATTTATAGAAATTGTTGAGACTTT
AAAAAATAATCCTTATAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATTTAGAGCGATATTCAAGAAGAATTA
ACCTTCAGCACAGGGTCGTCTATACCATAGATGATCGAAATAAAGTAGTATTAATACTATCGGCATGGTCACATTATGAT
TAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT228368 WP_003469323.1 NZ_CP089584:c4349914-4349762 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT228368 NZ_CP123853:2304079-2304336 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGTAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATGT
ATCTTGTATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References