Detailed information of TA system TA228367

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 1076150..1076655
• Replicon: chromosome
• Accession: NZ_CP089584
• Organism: Xanthomonas translucens pv. undulosa strain MAI5034

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LTC53_RS04820
• Protein ID: WP_058358982.1
• Coordinates: 1076150..1076407 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: LTC53_RS04825
• Protein ID: WP_003468816.1
• Coordinates: 1076404..1076655 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LTC53_RS04790 (LTC53_04790)	1071964..1072632	+	669	WP_058358980.1	dTMP kinase	-
LTC53_RS04795 (LTC53_04795)	1072629..1073606	+	978	WP_003468812.1	DNA polymerase III subunit delta'	-
LTC53_RS04800 (LTC53_04800)	1073603..1073956	+	354	WP_003468813.1	PilZ domain-containing protein	-
LTC53_RS04810 (LTC53_04810)	1074303..1074863	+	561	WP_141696960.1	hypothetical protein	-
LTC53_RS04815 (LTC53_04815)	1075147..1075791	+	645	WP_081318762.1	DUF4145 domain-containing protein	-
LTC53_RS04820 (LTC53_04820)	1076150..1076407	-	258	WP_058358982.1	Txe/YoeB family addiction module toxin	Toxin
LTC53_RS04825 (LTC53_04825)	1076404..1076655	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LTC53_RS04830 (LTC53_04830)	1076812..1077576	+	765	WP_068873280.1	DNA-formamidopyrimidine glycosylase family protein	-
LTC53_RS04835 (LTC53_04835)	1077573..1078295	-	723	WP_058359018.1	helix-turn-helix transcriptional regulator	-
LTC53_RS04840 (LTC53_04840)	1078419..1078868	+	450	WP_235049289.1	nuclear transport factor 2 family protein	-
LTC53_RS04845 (LTC53_04845)	1078872..1079726	+	855	WP_196479394.1	hypothetical protein	-
LTC53_RS04850 (LTC53_04850)	1079894..1080169	-	276	WP_003468826.1	hypothetical protein	-
LTC53_RS04855 (LTC53_04855)	1080504..1080794	+	291	WP_003468827.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10181.66 Da
• Isoelectric Point: 9.3936

>T228367 WP_058358982.1 NZ_CP089584:c1076407-1076150 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDDLYWQQTDKKMLKRVNDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINEEHRIVYRVEAGILLIAQV
RYHYL

Nucleotide

• Length: 258 bp

>T228367 NZ_CP123853:1191515-1191703 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT228367 WP_003468816.1 NZ_CP089584:c1076655-1076404 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT228367 NZ_CP123853:1191226-1191486 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTATATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9