Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 363120..363607 Replicon chromosome
Accession NZ_CP089532
Organism Pseudomonas veronii strain G2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LUW10_RS01585 Protein ID WP_198717758.1
Coordinates 363326..363607 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LUW10_RS01580 Protein ID WP_232591131.1
Coordinates 363120..363311 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUW10_RS01555 (LUW10_01555) 358615..359388 - 774 WP_017849951.1 ABC transporter ATP-binding protein -
LUW10_RS01560 (LUW10_01560) 359568..359753 + 186 WP_126585332.1 hypothetical protein -
LUW10_RS01565 (LUW10_01565) 359944..361335 + 1392 WP_017849950.1 GABA permease -
LUW10_RS01570 (LUW10_01570) 361476..361889 - 414 WP_046385011.1 hypothetical protein -
LUW10_RS01575 (LUW10_01575) 361959..362906 - 948 WP_126585333.1 alpha/beta fold hydrolase -
LUW10_RS01580 (LUW10_01580) 363120..363311 + 192 WP_232591131.1 antitoxin Antitoxin
LUW10_RS01585 (LUW10_01585) 363326..363607 + 282 WP_198717758.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LUW10_RS01590 (LUW10_01590) 363649..364623 + 975 WP_232591132.1 arsenic resistance protein -
LUW10_RS01595 (LUW10_01595) 364702..366309 + 1608 WP_232591133.1 hypothetical protein -
LUW10_RS01605 (LUW10_01605) 366632..366904 - 273 WP_017849944.1 oxidative damage protection protein -
LUW10_RS01610 (LUW10_01610) 366901..367968 - 1068 WP_193040721.1 A/G-specific adenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-79)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10590.23 Da        Isoelectric Point: 6.8474

>T228357 WP_198717758.1 NZ_CP089532:363326-363607 [Pseudomonas veronii]
IVALIEIIDYIEQYNPVAAVSLHQTIVVAAEGLSLMPYGFKHGRLSGTREMVVHPNYLVVYRVTEHVEIVMVLHTRQEYP
RDVIGPHHSTSRQ

Download         Length: 282 bp

>T228357 NZ_CP123852:c1174206-1173886 [Staphylococcus aureus]
ATGAATTGGGAAATTAAAGATTTAATGTGTGACATTGAAGTGATAAAACAAAAAATTAATGATGTAGCTACCAAACATGC
TTGGTTTGTTGAAGATAGATTTGTAAAAAATGAATTAGAAACAAAACGGGAACATATTAATTTTTCTGCTAGCTATTTAG
AACATCGTATACAAAATGAACATACAGTTGAGTTATTACAGGTTTATTTAAAAGAGTTCGATGAACTTATACAAAAATTT
CATGAAATAGAAAAAGCATCATCTGATGTAAGTTTGGCGACAGAATCAGATGACGCAAAGAAATTAAAAATTACAGAGTA
A

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7297.17 Da        Isoelectric Point: 5.8317

>AT228357 WP_232591131.1 NZ_CP089532:363120-363311 [Pseudomonas veronii]
MNIPRSPIVSEFETEEQAASYDRWFRAKVQASIDDPRPGIPHDQAMAEVEKVLEERRKARASR

Download         Length: 192 bp

>AT228357 NZ_CP123852:c1174418-1174209 [Staphylococcus aureus]
ATGAATAATGAACAAAAAGAAGTAATAGAACACGTGGTTTATCAACTTGAGTTAAGTGTCATGAATAATTTGGAAAGTTA
TGAACACACAGAATATGTTAATGGTATTGAAGTGGTTTCAGAGATCAGTCGTGAAAAGCACTTAGAATTGATAATGAAAT
GGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAGAAAGGAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References