Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2085962..2086130 Replicon chromosome
Accession NZ_CP089448
Organism Klebsiella michiganensis strain 8-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2086020..2086123 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2085962..2086130 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT930_RS09925 (LT930_09925) 2081089..2083149 + 2061 WP_033836507.1 oligopeptidase B -
LT930_RS09930 (LT930_09930) 2083156..2083815 - 660 WP_014229839.1 exodeoxyribonuclease X -
LT930_RS09935 (LT930_09935) 2083894..2084124 - 231 WP_004103351.1 DNA polymerase III subunit theta -
LT930_RS09940 (LT930_09940) 2084260..2084634 + 375 WP_014229838.1 CopC domain-containing protein YobA -
LT930_RS09945 (LT930_09945) 2084639..2085508 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
LT930_RS09950 (LT930_09950) 2085525..2085863 + 339 WP_064375491.1 YebY family protein -
- 2085962..2086130 - 169 - - Antitoxin
- 2086020..2086123 + 104 - - Toxin
LT930_RS09955 (LT930_09955) 2086248..2087207 - 960 WP_046878049.1 spore coat protein U domain-containing protein -
LT930_RS09960 (LT930_09960) 2087222..2089552 - 2331 WP_047723554.1 fimbria/pilus outer membrane usher protein -
LT930_RS09965 (LT930_09965) 2089555..2090319 - 765 WP_049102470.1 fimbria/pilus periplasmic chaperone -
LT930_RS09970 (LT930_09970) 2090338..2090856 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T228315 NZ_CP089448:2086020-2086123 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT228315 NZ_CP089448:c2086130-2085962 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References