Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 859893..860547 Replicon chromosome
Accession NZ_CP089437
Organism Citrobacter portucalensis strain GD21SC92T

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LT980_RS04150 Protein ID WP_003825515.1
Coordinates 860140..860547 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LT980_RS04145 Protein ID WP_003825514.1
Coordinates 859893..860159 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT980_RS04120 (LT980_04120) 855048..856481 - 1434 WP_250671734.1 6-phospho-beta-glucosidase BglA -
LT980_RS04125 (LT980_04125) 856602..857330 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
LT980_RS04130 (LT980_04130) 857383..857694 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
LT980_RS04135 (LT980_04135) 857858..858520 + 663 WP_071445549.1 hemolysin III family protein -
LT980_RS04140 (LT980_04140) 858652..859635 - 984 WP_250671735.1 tRNA-modifying protein YgfZ -
LT980_RS04145 (LT980_04145) 859893..860159 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
LT980_RS04150 (LT980_04150) 860140..860547 + 408 WP_003825515.1 protein YgfX Toxin
LT980_RS04155 (LT980_04155) 860649..861170 - 522 WP_003026933.1 flavodoxin FldB -
LT980_RS04160 (LT980_04160) 861284..862180 + 897 WP_250671736.1 site-specific tyrosine recombinase XerD -
LT980_RS04165 (LT980_04165) 862204..862917 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LT980_RS04170 (LT980_04170) 862923..864656 + 1734 WP_250671737.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T228233 WP_003825515.1 NZ_CP089437:860140-860547 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T228233 NZ_CP123547:c79159-78893 [Arsenophonus nasoniae]
TTGGTCTGGAAGATTAAATACGCTGATTCTGCACTGAAATCTCTAAAAAAAATGGATAGGCAGAATGCAAAAAGAATTGT
TGATTATCTCGATAAGCGCATAGCAAGTAGTGATGATCCTAGAATATTTGGAAAATCTCTTAAGGGTGACTTAGGTGAGT
TTTGGCGATACAGAATCGGTGATTATAGGGTGATTTGTGAAATTCTTGACGAAGAGTTAATTATTTTAGCTGCAATTATA
GGCCACCGTAGAGAAGTATATGAGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT228233 WP_003825514.1 NZ_CP089437:859893-860159 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT228233 NZ_CP123547:c79367-79143 [Arsenophonus nasoniae]
ATGTTGGCGATACGTCTACCGGATGAAATTGAAAATAGGTTAGATAATTTAGCAAAAAGAACAGGACGCACGAAGACATT
TTATGCCCGTGAAGCAATTCTTACGCATTTGGAGGATTTGGAAGATTACTACCTTGCTGCGAGTGTTGTTGCTCGTGTGC
GAAAAGGCCAAGATACGGTTCATAGTTCAGAGGATGTGAGGAAATCTCTTGGTCTGGAAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References