Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943842..1943987 Replicon chromosome
Accession NZ_CP089427
Organism Klebsiella pneumoniae strain 1194

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1943878..1943980 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943842..1943987 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9X66_RS09435 (A9X66_009435) 1938972..1941032 + 2061 WP_004151449.1 oligopeptidase B -
A9X66_RS09440 (A9X66_009440) 1941036..1941695 - 660 WP_032425085.1 exodeoxyribonuclease X -
A9X66_RS09445 (A9X66_009445) 1941774..1942004 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A9X66_RS09450 (A9X66_009450) 1942117..1942491 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A9X66_RS09455 (A9X66_009455) 1942495..1943364 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
A9X66_RS09460 (A9X66_009460) 1943381..1943719 + 339 WP_016529031.1 YebY family protein -
- 1943842..1943987 - 146 - - Antitoxin
- 1943878..1943980 + 103 - - Toxin
A9X66_RS09465 (A9X66_009465) 1944355..1944498 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A9X66_RS09470 (A9X66_009470) 1944603..1945571 - 969 WP_004151446.1 VirK/YbjX family protein -
A9X66_RS09475 (A9X66_009475) 1945728..1946381 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
A9X66_RS09480 (A9X66_009480) 1946378..1946569 - 192 WP_002911395.1 YebW family protein -
A9X66_RS09485 (A9X66_009485) 1946667..1946906 - 240 WP_002911393.1 YebV family protein -
A9X66_RS09490 (A9X66_009490) 1947022..1948455 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228213 NZ_CP089427:1943878-1943980 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228213 NZ_CP089427:c1943987-1943842 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References