Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2865665..2866221 Replicon chromosome
Accession NZ_CP089415
Organism Xanthomonas oryzae pv. oryzae strain GXO2016

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LUZ17_RS13560 Protein ID WP_229001948.1
Coordinates 2865665..2865916 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag LUZ17_RS13565 Protein ID WP_011408759.1
Coordinates 2865943..2866221 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUZ17_RS13520 (LUZ17_13520) 2861435..2862526 + 1092 WP_113195651.1 ribonuclease D -
LUZ17_RS13525 (LUZ17_13525) 2862602..2862939 - 338 Protein_2579 ATP-dependent DNA ligase -
LUZ17_RS13530 (LUZ17_13530) 2863221..2863397 - 177 Protein_2580 DUF3606 domain-containing protein -
LUZ17_RS13535 (LUZ17_13535) 2863619..2864020 + 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
LUZ17_RS23180 2864451..2864579 - 129 WP_012444694.1 hypothetical protein -
LUZ17_RS13545 (LUZ17_13545) 2864548..2864667 - 120 Protein_2583 IS3 family transposase -
LUZ17_RS13550 (LUZ17_13550) 2864884..2865138 - 255 WP_223293127.1 hypothetical protein -
LUZ17_RS23185 2865207..2865341 - 135 WP_011051575.1 hypothetical protein -
LUZ17_RS13555 (LUZ17_13555) 2865334..2865588 - 255 WP_198912806.1 hypothetical protein -
LUZ17_RS13560 (LUZ17_13560) 2865665..2865916 - 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LUZ17_RS13565 (LUZ17_13565) 2865943..2866221 - 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
LUZ17_RS13570 (LUZ17_13570) 2866417..2866761 - 345 WP_199285675.1 hypothetical protein -
LUZ17_RS13575 (LUZ17_13575) 2867667..2868851 - 1185 WP_011408760.1 IS256-like element IS1113 family transposase -
LUZ17_RS13580 (LUZ17_13580) 2869432..2870397 + 966 WP_109181928.1 IS1595-like element ISXo5 family transposase -
LUZ17_RS13585 (LUZ17_13585) 2870547..2871104 + 558 WP_011259349.1 DNA-3-methyladenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T228206 WP_229001948.1 NZ_CP089415:c2865916-2865665 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T228206 NZ_CP123499:c1578287-1576971 [Arsenophonus sp. aPb]
ATGGTAATGGAAGTTATCAATGTCACCTATAAGCAACATGAAGTGGGTGCAGTAAGTTTTGATACTAGCAAAGGTTTAGG
TTTTTTTGAATACAATGCCAGCTTTATCAAACAGGGAATCGAGTTATCGCCACTGAAAATGCCATTAGCAACGCGAATTT
ATAGTTTTCCCGAATTGGATTTTAATACCTTTAAAGGATTACCTGGTTTAATTGCTGACTCGTTACCCGATGACTTTGGT
AATGCGGTACTTAATGCTTGGGTTGCGACGATGGGTAAATCGCCTGACACCATTACGCCATTACAGCGACTACAATATAC
CGGTAAAAGAGGGATGGGCGCGTTAGAATACGTGCCAGCAACTAGGATCAAAAGTCTCAATGCCTCACAACACGTTGAGA
TCAGTTCTCTGGTTGCTATCACTCAAGAAATTCTTGATTCAAGGCAAAAATTTACCGTTGAGCTGCATAAAAATGGTCAG
GAAGATCGCGAAGCAATGATGGCACTGCTTTCAGTTGGCATGAGTGCTGGTGGCGCGAGACCAAAAGCCGTTCTTGCTTT
TAATCACGATTTCACCCAGGTTCGTTCGGGACAAACTAATGTTCCGGACGGTTTTACCCATTATTTAATAAAGTTCGATG
GTGTTAGTGAACATAATAAAAATCAACAAACCTTTGGTGATCCAGTCGGTTTTGGTGCAATGGAATATGTTTATTATTTA
TTGGCAACCCGCTGTGGCATAGAAATGATGCCTTGCCGGCTGCTCGCTGAAGGTAATAGACGCCATTTTATTACTCAGCG
CTTTGATCGTTTTGGTAATAAAAAACGCCATGTACAAACCTTAAATGGCCTTGCTCACGTTGATTACAAAAAACCCGGCT
CTTTCTCCTACGCCGAATTATTCGCTGTTGCTAGACAATTAAAACTTTCAGCAAAAGAGGCAGAACAACTACTAAAAAGA
ATGACCTTTAATATTGTAGCTCGTAACCATGATGATCACGCTAAAAATTTTTCTTTTATGTTAAAAGGCGATAAGTGGAT
GCTAGCCCCTGCCTACGATTTAGCTTATAGCTACAAGCCCGGTAGTAAATGGGTAAACAGTCATTGGATGAGCTTAAATG
GGAAACGTGACAACTTTTCTCGCCAAGATTTTTACTCATTAGAAAAACTAAGTCCCCTATTTACCCGAGAAATGATCAAC
GGAATTATTGATGAAACGATAGAGAAAGTTTCACAGTGGCAAAAACTAGCTGTTGAATTTGAAGTGCCTAATTTGTTAGC
GCAGGAAATTAACGCAAATTTATGTTTAAATATCTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT228206 WP_011408759.1 NZ_CP089415:c2866221-2865943 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT228206 NZ_CP123499:c1578610-1578281 [Arsenophonus sp. aPb]
ATGAGCATATTTGAAAAATCAGCTTCAGCGATCGCAGCGGAATTAGGCGAACGTTTGAAACAAGCTCGATTAAATCATGA
TTTAACTCAAGCTGAAGTAGCTGAAATGTCCGGTATCAGTCGAAAAACGGTCCTAAATGCAGAAAAAGGTAACGTCCAAT
TAGAGAACTTAATCGCTATTATGGCAGCATTGAATTTGCTTGAACAATTAGATCTATTGTTGCCTAAACAGGATATCTCA
CCTATTCAACTTGCTAAGTTACAGGGTAAAAAAAGACAACGCGCATCTGGGCAGAGAAAAAATAATACAGAGGATTTAGC
AGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References