228204

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 427097..427447 Replicon chromosome
Accession NZ_CP089415
Organism Xanthomonas oryzae pv. oryzae strain GXO2016

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LUZ17_RS02015 Protein ID WP_011257368.1
Coordinates 427313..427447 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LUZ17_RS02010 Protein ID WP_011407410.1
Coordinates 427097..427249 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUZ17_RS01985 (LUZ17_01985) 423377..424060 - 684 WP_011257363.1 dTMP kinase -
LUZ17_RS01990 (LUZ17_01990) 424540..425082 - 543 Protein_381 GTPase -
LUZ17_RS01995 (LUZ17_01995) 425079..425534 - 456 Protein_382 hypothetical protein -
LUZ17_RS02000 (LUZ17_02000) 425526..425744 - 219 Protein_383 hypothetical protein -
LUZ17_RS02005 (LUZ17_02005) 426066..426989 + 924 WP_011407409.1 arginase -
LUZ17_RS02010 (LUZ17_02010) 427097..427249 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LUZ17_RS02015 (LUZ17_02015) 427313..427447 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LUZ17_RS02020 (LUZ17_02020) 427688..427897 + 210 WP_011407411.1 CsbD family protein -
LUZ17_RS02025 (LUZ17_02025) 428066..429355 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
LUZ17_RS02030 (LUZ17_02030) 429486..430430 + 945 WP_113195610.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T228204 WP_011257368.1 NZ_CP089415:427313-427447 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T228204 NZ_CP123499:c1163604-1163347 [Arsenophonus sp. aPb]
ATGAAATTAATATTTACCGAACAATCATGGAACGATTACCTTTATTGGCAGCAGATAGATAAAAAGATAATTAAACGTAT
TAATGAATTAATTAAAGATATTAAAAGAGAACCTTTTTCTGGTATAGGTAAGCCAGAGCCTTTAAAACACAATTTAACCG
CTTTTTGGTCGCGCAGAATAACTGAGGAACATCGTTTAATTTACCGGTTAACAGATAAGGGCTTAGAGATAGCTTCATGT
CGTTATTACTATAATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT228204 WP_011407410.1 NZ_CP089415:427097-427249 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT228204 NZ_CP123499:c1163852-1163601 [Arsenophonus sp. aPb]
ATGAAAACAGTCAATTATACCGATGCAAGACAAAACTTAACCTCTATCATGAATGAAGCAATAGATGATCGGATCCCAAT
TTTAATCACTAGACAAAAAGGGATTCCTTGCGTTTTGTTATCCCTTGATGAATACCAATCTTTAGAAGAGACGGCCTACT
TGCTGCGCTCGCCAGCTAATGCTCGTCATCTATTGGATTCAATTGATGAACTCAATGCCGGTAAAGGAATTGAAAGAGAT
ATTCAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References