Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 716989..717761 Replicon chromosome
Accession NZ_CP089414
Organism Dyella terrae strain Ely Copper Mine

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag DYST_RS02870 Protein ID WP_239949903.1
Coordinates 717261..717761 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag DYST_RS02865 Protein ID WP_239949901.1
Coordinates 716989..717264 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYST_RS02850 (DYST_00585) 712288..712647 - 360 WP_239949895.1 helix-turn-helix domain-containing protein -
DYST_RS02855 (DYST_00586) 712797..715835 + 3039 WP_239949897.1 CHC2 zinc finger domain-containing protein -
DYST_RS02860 (DYST_00587) 715840..716949 + 1110 WP_239949899.1 site-specific tyrosine recombinase XerC -
DYST_RS02865 (DYST_00588) 716989..717264 + 276 WP_239949901.1 DUF1778 domain-containing protein Antitoxin
DYST_RS02870 (DYST_00589) 717261..717761 + 501 WP_239949903.1 GNAT family N-acetyltransferase Toxin
DYST_RS02875 (DYST_00590) 718080..719201 + 1122 WP_239949905.1 hypothetical protein -
DYST_RS02880 (DYST_00591) 719183..719539 + 357 WP_239949907.1 hypothetical protein -
DYST_RS02885 (DYST_00592) 719571..719999 + 429 WP_239949908.1 hypothetical protein -
DYST_RS02890 (DYST_00594) 720585..720977 - 393 WP_239949910.1 hypothetical protein -
DYST_RS02895 (DYST_00595) 721441..722592 + 1152 WP_239949912.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-146)

Antitoxin

Vibrio phage ICP1, Orf50

(6-90)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18159.07 Da        Isoelectric Point: 8.5090

>T228202 WP_239949903.1 NZ_CP089414:717261-717761 [Dyella terrae]
VKRPPLRAPAPLADAHRLDDFRCTEPALETWLKQRARRNQLDGASRCYVVCAGEDVVGYYALAAGAVSHEQAPGNVRRNM
PDPIPVIVLGRLAVHADWSGQGIGAGLLKDAVLRALRLSQEMGIRALLCHAINEDAKRFYLHHGFVVSPIEPLTVMLNLA
KVPTID

Download         Length: 501 bp

>T228202 NZ_CP123498:c2080024-2079617 [Arsenophonus nasoniae]
GTGGTTCTTTGGAAATTTAATATCAATGTTTCGTGGCTGACGCAGCTTTTTTCAACGGGTGTTCATGTGGGAATTGGCTT
GTTAGTTTTCTTTTCATCTTGGCCACCAAATAATCTGGTCACTTGGTTGATAGCGACCTTATTGATTGTGGCAAGTTGGG
TAAGGAGTCAAAAAAATATTAGTCGTTGTAAAGGTAGCATAGTTTTACTTAATGGTAATAAGATACAGTGGAAAAAAAGC
GAATGGCTGATTGTTAAAAAACCTTGGTTTTGTTTTTTTGGTGTAAAACTTACTCTTCGTTCATGGCAATGTAATAAGCG
GATTCGGTTATGGATTGCTTCAGATAGTATGCCAGAAGAGGAATGGCGGAATTTAAATCAATTGCTGTTGCAGTACCCTG
ATATTTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10133.74 Da        Isoelectric Point: 11.4224

>AT228202 WP_239949901.1 NZ_CP089414:716989-717264 [Dyella terrae]
MTTVARQTTINLRAQAPQRSLIDQAARVAGKSRTDFMLEAACEKAQQVLLDQTVFALDATRFKRFQALLDAPVAHGAALR
KLLRRQAPWEA

Download         Length: 276 bp

>AT228202 NZ_CP123498:c2080271-2080005 [Arsenophonus nasoniae]
ATGGATATCAATCATAAACCCAGGATCCACTGGGCATGTCGCAGAGGAATGCGTGAGTTGGACATCGCCATTATGCCTTT
TTTTGAGTATGAATATGATTCACTCACAGAGGATGAGAAATGTCTGTTTGTTCGTTTACTAGAGTGTGCAGATCCTGATT
TGTTCAACTGGTTGATGAATCATGGGCGTCCTGATGATGATGGTCTTTATCATATGATTCAATTGATACAGAGTAGAAAT
AAACAACGTGGTTCTTTGGAAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References