Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 397394..398052 Replicon chromosome
Accession NZ_CP089391
Organism Bradyrhizobium sp. 14AB

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I3J27_RS01925 Protein ID WP_270164607.1
Coordinates 397394..397798 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I3J27_RS01930 Protein ID WP_270164609.1
Coordinates 397798..398052 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I3J27_RS01905 (I3J27_01905) 392686..395256 - 2571 WP_270164601.1 FtsX-like permease family protein -
I3J27_RS01910 (I3J27_01910) 395253..395975 - 723 WP_270164603.1 ABC transporter ATP-binding protein -
I3J27_RS01915 (I3J27_01915) 396031..396666 + 636 WP_270173017.1 arylesterase -
I3J27_RS01920 (I3J27_01920) 396841..397377 + 537 WP_270164605.1 RNA 2',3'-cyclic phosphodiesterase -
I3J27_RS01925 (I3J27_01925) 397394..397798 - 405 WP_270164607.1 type II toxin-antitoxin system VapC family toxin Toxin
I3J27_RS01930 (I3J27_01930) 397798..398052 - 255 WP_270164609.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
I3J27_RS01935 (I3J27_01935) 398249..399433 + 1185 WP_270164611.1 cell division protein ZapE -
I3J27_RS01940 (I3J27_01940) 399624..400592 + 969 WP_151646186.1 malate dehydrogenase -
I3J27_RS01945 (I3J27_01945) 400798..401994 + 1197 WP_270164618.1 ADP-forming succinate--CoA ligase subunit beta -
I3J27_RS01950 (I3J27_01950) 401999..402478 + 480 WP_270164621.1 DUF1579 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(2-83)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14320.33 Da        Isoelectric Point: 4.7590

>T228151 WP_270164607.1 NZ_CP089391:c397798-397394 [Bradyrhizobium sp. 14AB]
MVIDTSAIVAIALNEADAANIERLIADDPIRLISAATVLEATMVIETRLGDAGGREFDLWLVKIGAEVVAVDAEQADAAR
RAWRRCGKGRHVASLNYGDCFSYALAMTRGEALLFKGEDFAKTDVSRAGGAPPR

Download         Length: 405 bp

>T228151 NZ_CP123365:c3224691-3224377 [Shigella flexneri]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9606.86 Da        Isoelectric Point: 4.9120

>AT228151 WP_270164609.1 NZ_CP089391:c398052-397798 [Bradyrhizobium sp. 14AB]
VALSIKDPETEQLARSLAQLTGETITTATKRAIEERLRRLGGQARKDALLEDMAEIRRRWSEMRVVDDRTPEQILGYDED
GLPR

Download         Length: 255 bp

>AT228151 NZ_CP123365:c3224380-3223964 [Shigella flexneri]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References