Detailed information of TA system TA022815

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 2756047..2756689
• Replicon: chromosome
• Accession: NC_010581
• Organism: Beijerinckia indica subsp. indica ATCC 9039

Toxin (Protein)

• Gene name: relE
• Uniprot ID: B2IHY1
• Locus tag: BIND_RS12205
• Protein ID: WP_012385377.1
• Coordinates: 2756438..2756689 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BIND_RS12200
• Protein ID: WP_012385376.1
• Coordinates: 2756047..2756436 (-)
• Length: 130 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BIND_RS12180	2752226..2753707	+	1482	WP_012385374.1	YcjX family protein	-
BIND_RS12185	2753707..2754798	+	1092	WP_012385375.1	TIGR01620 family protein	-
BIND_RS20625	2754901..2755852	-	952	Protein_2387	IS630 family transposase	-
BIND_RS21335	2755851..2756036	+	186	WP_148210627.1	hypothetical protein	-
BIND_RS12200	2756047..2756436	-	390	WP_012385376.1	helix-turn-helix transcriptional regulator	Antitoxin
BIND_RS12205	2756438..2756689	-	252	WP_012385377.1	plasmid stabilization protein	Toxin
BIND_RS12210	2756777..2757763	-	987	WP_012385378.1	transporter	-
BIND_RS12215	2758065..2758640	-	576	WP_012385379.1	hypothetical protein	-
BIND_RS12225	2759397..2760416	-	1020	WP_012385380.1	ketol-acid reductoisomerase	-
BIND_RS12230	2760553..2761104	-	552	WP_041778776.1	acetolactate synthase small subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (73-127)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9354.65 Da
• Isoelectric Point: 9.7606

>T22815 WP_012385377.1 NC_010581:c2756689-2756438 [Beijerinckia indica subsp. indica ATCC 9039]
VKTIIFTHRAAKELDAIEGDAREAIVAALHDYAVDGRGDVKALSGRSGYRLRIGRYRVIFDEDKVTILALYIGKRETTTY
RNN

Nucleotide

• Length: 252 bp

>T22815 NC_010581:c2756689-2756438 [Beijerinckia indica subsp. indica ATCC 9039]
GTGAAGACGATCATTTTTACCCACAGAGCTGCCAAGGAGCTTGACGCGATTGAGGGCGACGCCCGCGAAGCGATCGTGGC
TGCTTTGCATGATTATGCCGTTGATGGGCGCGGCGATGTGAAAGCGCTTTCTGGACGTAGTGGTTATCGTCTTCGTATTG
GCCGCTATCGGGTGATTTTTGACGAAGATAAAGTCACCATTCTCGCGCTTTATATTGGTAAGCGTGAAACAACAACCTAT
CGGAATAACTGA

Antitoxin

Protein

• Length: 130 a.a.
• Molecular weight: 13919.69 Da
• Isoelectric Point: 4.3035

>AT22815 WP_012385376.1 NC_010581:c2756436-2756047 [Beijerinckia indica subsp. indica ATCC 9039]
MRAPQIIRTAAGEELVVIPKSDYDELIAAYSEAEEDAADLAIYDARKKELEEGSNAALPAEVSASLLRGDSLLKAFRKWR
GMTQIDLAKAAGLGQGYLSDLESRRRGGTPETLASLATALDIDPAWLVE

Nucleotide

• Length: 390 bp

>AT22815 NC_010581:c2756436-2756047 [Beijerinckia indica subsp. indica ATCC 9039]
ATGCGCGCGCCACAAATCATTAGGACGGCAGCCGGAGAGGAATTGGTCGTCATTCCCAAGAGTGATTATGACGAACTCAT
CGCGGCCTATTCAGAGGCTGAAGAGGATGCTGCTGATCTCGCTATATATGATGCCCGCAAGAAGGAACTCGAGGAAGGAT
CTAATGCGGCTCTCCCGGCGGAGGTCAGCGCCAGCCTTTTGCGCGGCGACAGCCTATTGAAGGCGTTTCGCAAGTGGCGC
GGTATGACGCAAATCGATCTGGCGAAAGCCGCGGGTCTCGGACAAGGATACCTCTCTGATTTAGAGAGCCGACGCAGAGG
TGGCACGCCAGAAACGCTTGCTTCGCTTGCCACAGCTTTGGATATTGATCCGGCATGGCTGGTTGAATAA

Structures

Toxin

• AlphaFold DB: B2IHY1