Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 1711370..1712340 | Replicon | chromosome |
| Accession | NC_010581 | ||
| Organism | Beijerinckia indica subsp. indica ATCC 9039 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | B2IB59 |
| Locus tag | BIND_RS07660 | Protein ID | WP_012384500.1 |
| Coordinates | 1711370..1711855 (-) | Length | 162 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | B2IB60 |
| Locus tag | BIND_RS07665 | Protein ID | WP_012384501.1 |
| Coordinates | 1711852..1712340 (-) | Length | 163 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BIND_RS07645 | 1707450..1708808 | + | 1359 | WP_012384497.1 | pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase | - |
| BIND_RS07650 | 1708860..1710302 | + | 1443 | WP_012384498.1 | dihydrolipoyl dehydrogenase | - |
| BIND_RS07655 | 1710367..1711344 | + | 978 | WP_012384499.1 | lipoyl synthase | - |
| BIND_RS07660 | 1711370..1711855 | - | 486 | WP_012384500.1 | RES family NAD+ phosphorylase | Toxin |
| BIND_RS07665 | 1711852..1712340 | - | 489 | WP_012384501.1 | DUF2384 domain-containing protein | Antitoxin |
| BIND_RS07670 | 1712430..1712888 | + | 459 | WP_012384502.1 | ubiquinone-binding protein | - |
| BIND_RS07675 | 1712896..1714068 | - | 1173 | WP_012384503.1 | MFS transporter | - |
| BIND_RS07680 | 1714188..1714691 | - | 504 | WP_012384504.1 | CinA family protein | - |
| BIND_RS07685 | 1714688..1715407 | - | 720 | WP_148210748.1 | HAD family hydrolase | - |
| BIND_RS07690 | 1715484..1716710 | - | 1227 | WP_012384506.1 | bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 17736.33 Da Isoelectric Point: 9.4809
>T22814 WP_012384500.1 NC_010581:c1711855-1711370 [Beijerinckia indica subsp. indica ATCC 9039]
MSRTVWRIATDTPNYEADDLSGAGAKITGGRWNRAGVPVIYTSETRALACLETMVHFNAGGLPLNRYLVALSIPDEIWAD
AQRENPASLKVGWDAEPAGRASITFGTDWLQSKRSALLIVPSVIVPEEFNVLINPQHPALARITATKVRKWLYDPRLGKK
P
MSRTVWRIATDTPNYEADDLSGAGAKITGGRWNRAGVPVIYTSETRALACLETMVHFNAGGLPLNRYLVALSIPDEIWAD
AQRENPASLKVGWDAEPAGRASITFGTDWLQSKRSALLIVPSVIVPEEFNVLINPQHPALARITATKVRKWLYDPRLGKK
P
Download Length: 486 bp
>T22814 NC_010581:c1711855-1711370 [Beijerinckia indica subsp. indica ATCC 9039]
ATGAGTCGCACCGTCTGGCGGATCGCAACCGACACACCGAACTACGAGGCGGATGACCTGTCGGGAGCGGGCGCAAAGAT
AACAGGCGGACGCTGGAACAGAGCCGGCGTCCCGGTCATCTATACCTCGGAAACACGGGCCCTGGCCTGCCTGGAAACAA
TGGTCCATTTCAATGCAGGTGGCCTTCCTCTCAATCGCTACCTCGTCGCGCTATCCATCCCGGACGAGATATGGGCTGAT
GCCCAGCGGGAAAATCCTGCTAGTTTAAAGGTCGGCTGGGACGCCGAGCCGGCGGGGCGGGCCAGCATCACCTTCGGAAC
GGACTGGCTTCAATCGAAAAGGTCGGCGCTGCTCATCGTCCCTTCCGTCATCGTGCCGGAAGAATTCAACGTCCTCATCA
ATCCCCAGCATCCAGCCCTTGCGCGGATTACGGCCACCAAGGTCCGCAAATGGCTTTATGATCCGCGCCTTGGCAAAAAG
CCTTGA
ATGAGTCGCACCGTCTGGCGGATCGCAACCGACACACCGAACTACGAGGCGGATGACCTGTCGGGAGCGGGCGCAAAGAT
AACAGGCGGACGCTGGAACAGAGCCGGCGTCCCGGTCATCTATACCTCGGAAACACGGGCCCTGGCCTGCCTGGAAACAA
TGGTCCATTTCAATGCAGGTGGCCTTCCTCTCAATCGCTACCTCGTCGCGCTATCCATCCCGGACGAGATATGGGCTGAT
GCCCAGCGGGAAAATCCTGCTAGTTTAAAGGTCGGCTGGGACGCCGAGCCGGCGGGGCGGGCCAGCATCACCTTCGGAAC
GGACTGGCTTCAATCGAAAAGGTCGGCGCTGCTCATCGTCCCTTCCGTCATCGTGCCGGAAGAATTCAACGTCCTCATCA
ATCCCCAGCATCCAGCCCTTGCGCGGATTACGGCCACCAAGGTCCGCAAATGGCTTTATGATCCGCGCCTTGGCAAAAAG
CCTTGA
Antitoxin
Download Length: 163 a.a. Molecular weight: 17167.74 Da Isoelectric Point: 5.9278
>AT22814 WP_012384501.1 NC_010581:c1712340-1711852 [Beijerinckia indica subsp. indica ATCC 9039]
MSSKPSAQPVSLAAAQSQPAALSYLAVYRASPFERIAMIKRGISATEAKRMFAHLNLGQGAALKALNLSPATVNKKAKRD
ETLSPEESERVIGIAKLVGQLEAMVEESGNAEGFDATAWIARWLMEPLPALGGARPVELMDTMEGQALVAETLAQIQSGA
YA
MSSKPSAQPVSLAAAQSQPAALSYLAVYRASPFERIAMIKRGISATEAKRMFAHLNLGQGAALKALNLSPATVNKKAKRD
ETLSPEESERVIGIAKLVGQLEAMVEESGNAEGFDATAWIARWLMEPLPALGGARPVELMDTMEGQALVAETLAQIQSGA
YA
Download Length: 489 bp
>AT22814 NC_010581:c1712340-1711852 [Beijerinckia indica subsp. indica ATCC 9039]
ATGTCTTCAAAACCCTCGGCTCAACCCGTGTCCCTTGCAGCGGCCCAGTCCCAGCCCGCCGCACTGTCTTATCTGGCCGT
CTATCGCGCCTCCCCGTTCGAGCGGATCGCCATGATCAAGCGCGGCATAAGCGCCACCGAAGCAAAGCGCATGTTCGCTC
ACCTCAATCTAGGCCAGGGCGCGGCGCTTAAAGCCCTGAATCTCTCTCCCGCCACCGTCAACAAGAAAGCGAAGCGGGAT
GAGACCCTATCGCCCGAGGAGAGCGAACGCGTCATCGGAATCGCCAAGCTGGTCGGCCAATTGGAGGCCATGGTCGAGGA
ATCGGGCAATGCCGAAGGGTTTGATGCGACCGCCTGGATTGCGCGCTGGCTGATGGAGCCCCTGCCGGCCTTGGGCGGTG
CGCGGCCTGTCGAACTGATGGACACGATGGAGGGGCAGGCTCTGGTGGCCGAGACGCTTGCGCAGATACAGAGCGGTGCC
TACGCATGA
ATGTCTTCAAAACCCTCGGCTCAACCCGTGTCCCTTGCAGCGGCCCAGTCCCAGCCCGCCGCACTGTCTTATCTGGCCGT
CTATCGCGCCTCCCCGTTCGAGCGGATCGCCATGATCAAGCGCGGCATAAGCGCCACCGAAGCAAAGCGCATGTTCGCTC
ACCTCAATCTAGGCCAGGGCGCGGCGCTTAAAGCCCTGAATCTCTCTCCCGCCACCGTCAACAAGAAAGCGAAGCGGGAT
GAGACCCTATCGCCCGAGGAGAGCGAACGCGTCATCGGAATCGCCAAGCTGGTCGGCCAATTGGAGGCCATGGTCGAGGA
ATCGGGCAATGCCGAAGGGTTTGATGCGACCGCCTGGATTGCGCGCTGGCTGATGGAGCCCCTGCCGGCCTTGGGCGGTG
CGCGGCCTGTCGAACTGATGGACACGATGGAGGGGCAGGCTCTGGTGGCCGAGACGCTTGCGCAGATACAGAGCGGTGCC
TACGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|