Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018031..2018175 Replicon chromosome
Accession NZ_CP089385
Organism Klebsiella variicola subsp. variicola strain KPN692

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018067..2018169 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018031..2018175 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUX40_RS09680 (LUX40_09680) 2013161..2015221 + 2061 WP_012541258.1 oligopeptidase B -
LUX40_RS09685 (LUX40_09685) 2015225..2015884 - 660 WP_008804267.1 exodeoxyribonuclease X -
LUX40_RS09690 (LUX40_09690) 2015963..2016193 - 231 WP_012541260.1 DNA polymerase III subunit theta -
LUX40_RS09695 (LUX40_09695) 2016307..2016681 + 375 WP_038421459.1 CopC domain-containing protein YobA -
LUX40_RS09700 (LUX40_09700) 2016685..2017554 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
LUX40_RS09705 (LUX40_09705) 2017571..2017909 + 339 WP_004189269.1 YebY family protein -
- 2018031..2018175 - 145 - - Antitoxin
- 2018067..2018169 + 103 - - Toxin
LUX40_RS09710 (LUX40_09710) 2018554..2018697 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
LUX40_RS09715 (LUX40_09715) 2018801..2019769 - 969 WP_162493241.1 VirK/YbjX family protein -
LUX40_RS09720 (LUX40_09720) 2019926..2020579 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
LUX40_RS09725 (LUX40_09725) 2020576..2020767 - 192 WP_002911395.1 YebW family protein -
LUX40_RS09730 (LUX40_09730) 2020865..2021104 - 240 WP_002911393.1 YebV family protein -
LUX40_RS09735 (LUX40_09735) 2021220..2022653 - 1434 WP_232393220.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228136 NZ_CP089385:2018067-2018169 [Klebsiella variicola subsp. variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT228136 NZ_CP089385:c2018175-2018031 [Klebsiella variicola subsp. variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References