Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1839212..1839357 Replicon chromosome
Accession NZ_CP089383
Organism Klebsiella pneumoniae strain KPN342

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1839248..1839350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1839212..1839357 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUX38_RS08920 1834342..1836402 + 2061 WP_004151449.1 oligopeptidase B -
LUX38_RS08925 1836406..1837065 - 660 WP_002911407.1 exodeoxyribonuclease X -
LUX38_RS08930 1837144..1837374 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LUX38_RS08935 1837487..1837861 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LUX38_RS08940 1837865..1838734 + 870 WP_004184661.1 copper homeostasis membrane protein CopD -
LUX38_RS08945 1838751..1839089 + 339 WP_002911404.1 YebY family protein -
- 1839212..1839357 - 146 - - Antitoxin
- 1839248..1839350 + 103 - - Toxin
LUX38_RS08950 1839725..1839868 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LUX38_RS08955 1839973..1840941 - 969 WP_014907334.1 VirK/YbjX family protein -
LUX38_RS08960 1841098..1841751 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
LUX38_RS08965 1841748..1841939 - 192 WP_002911395.1 YebW family protein -
LUX38_RS08970 1842037..1842276 - 240 WP_002911393.1 YebV family protein -
LUX38_RS08975 1842392..1843825 - 1434 WP_232410813.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T228114 NZ_CP089383:1839248-1839350 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT228114 NZ_CP089383:c1839357-1839212 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References