Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3163789..3164450 Replicon chromosome
Accession NZ_CP089316
Organism Citrobacter portucalensis strain K218

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag LT989_RS15700 Protein ID WP_125112788.1
Coordinates 3164130..3164450 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LT989_RS15695 Protein ID WP_125112787.1
Coordinates 3163789..3164109 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT989_RS15650 (3158932) 3158932..3159756 + 825 WP_125112781.1 DUF932 domain-containing protein -
LT989_RS15655 (3159965) 3159965..3160675 + 711 WP_125112782.1 DeoR family transcriptional regulator -
LT989_RS15660 (3160701) 3160701..3161237 + 537 WP_059384881.1 DUF4339 domain-containing protein -
LT989_RS15665 (3161279) 3161279..3161716 + 438 WP_125112783.1 hypothetical protein -
LT989_RS15670 (3161658) 3161658..3162191 + 534 WP_232397702.1 hypothetical protein -
LT989_RS15675 (3162269) 3162269..3162505 + 237 WP_125112785.1 DUF905 domain-containing protein -
LT989_RS15680 (3162591) 3162591..3163049 + 459 Protein_3080 antirestriction protein -
LT989_RS15685 (3163058) 3163058..3163540 + 483 WP_125112786.1 DNA repair protein RadC -
LT989_RS15690 (3163549) 3163549..3163770 + 222 Protein_3082 DUF987 domain-containing protein -
LT989_RS15695 (3163789) 3163789..3164109 + 321 WP_125112787.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LT989_RS15700 (3164130) 3164130..3164450 + 321 WP_125112788.1 TA system toxin CbtA family protein Toxin
LT989_RS15705 (3164807) 3164807..3164965 + 159 Protein_3085 integrase -
LT989_RS15710 (3165212) 3165212..3166093 + 882 WP_063941013.1 hypothetical protein -
LT989_RS15715 (3166642) 3166642..3166998 + 357 WP_125112789.1 hypothetical protein -
LT989_RS15720 (3167193) 3167193..3168011 - 819 WP_048215741.1 5-deoxy-glucuronate isomerase -
LT989_RS15725 (3168021) 3168021..3168911 - 891 WP_125112835.1 myo-inosose-2 dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3145129..3166093 20964


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-104)

Antitoxin

Antitoxin CbeA

(6-105)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12103.16 Da        Isoelectric Point: 9.6861

>T228072 WP_125112788.1 NZ_CP089316:3164130-3164450 [Citrobacter portucalensis]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLKQHYGLTLNDTPFSDETVIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAMREMRT

Download         Length: 321 bp

>T228072 NZ_CP123266:3638436-3638978 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12004.68 Da        Isoelectric Point: 6.9461

>AT228072 WP_125112787.1 NZ_CP089316:3163789-3164109 [Citrobacter portucalensis]
MRSNVTWGLLRDITPRLGARLVQEGNRLHYLADRASFTGTFSETECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTLY
HNGFTCEADTLGSCGYVYIAVYLTQR

Download         Length: 321 bp

>AT228072 NZ_CP123266:3638141-3638452 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
TGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References