Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2182158..2182326 Replicon chromosome
Accession NZ_CP089315
Organism Klebsiella michiganensis strain K92

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2182216..2182319 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2182158..2182326 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT984_RS10440 (LT984_10440) 2177285..2179345 + 2061 WP_014229840.1 oligopeptidase B -
LT984_RS10445 (LT984_10445) 2179352..2180011 - 660 WP_014229839.1 exodeoxyribonuclease X -
LT984_RS10450 (LT984_10450) 2180090..2180320 - 231 WP_004103351.1 DNA polymerase III subunit theta -
LT984_RS10455 (LT984_10455) 2180456..2180830 + 375 WP_014229838.1 CopC domain-containing protein YobA -
LT984_RS10460 (LT984_10460) 2180835..2181704 + 870 WP_089046373.1 copper homeostasis membrane protein CopD -
LT984_RS10465 (LT984_10465) 2181721..2182059 + 339 WP_004103344.1 YebY family protein -
- 2182158..2182326 - 169 - - Antitoxin
- 2182216..2182319 + 104 - - Toxin
LT984_RS10470 (LT984_10470) 2182444..2183403 - 960 WP_014229836.1 spore coat protein U domain-containing protein -
LT984_RS10475 (LT984_10475) 2183418..2185748 - 2331 WP_014838820.1 fimbria/pilus outer membrane usher protein -
LT984_RS10480 (LT984_10480) 2185751..2186515 - 765 WP_014229834.1 fimbria/pilus periplasmic chaperone -
LT984_RS10485 (LT984_10485) 2186534..2187052 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T228048 NZ_CP089315:2182216-2182319 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT228048 NZ_CP089315:c2182326-2182158 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References