Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-PHA01976
Location 1388116..1388706 Replicon chromosome
Accession NZ_CP089311
Organism Aureimonas altamirensis strain C2P003

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LUX29_RS06785 Protein ID WP_232414299.1
Coordinates 1388458..1388706 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LUX29_RS06780 Protein ID WP_232414298.1
Coordinates 1388116..1388436 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUX29_RS06755 (LUX29_06755) 1383840..1385477 + 1638 WP_232414294.1 acyl-CoA synthetase -
LUX29_RS06760 (LUX29_06760) 1385467..1385985 - 519 WP_060604448.1 gamma-glutamylcyclotransferase -
LUX29_RS06765 (LUX29_06765) 1386033..1387046 + 1014 WP_232414295.1 DUF2125 domain-containing protein -
LUX29_RS06770 (LUX29_06770) 1387083..1387832 - 750 WP_232414296.1 SIMPL domain-containing protein -
LUX29_RS06780 (LUX29_06780) 1388116..1388436 - 321 WP_232414298.1 helix-turn-helix transcriptional regulator Antitoxin
LUX29_RS06785 (LUX29_06785) 1388458..1388706 - 249 WP_232414299.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LUX29_RS06790 (LUX29_06790) 1388840..1389469 - 630 WP_232414300.1 XRE family transcriptional regulator -
LUX29_RS06795 (LUX29_06795) 1389683..1390705 + 1023 WP_232414302.1 Ldh family oxidoreductase -
LUX29_RS06800 (LUX29_06800) 1390702..1392003 + 1302 WP_232414304.1 MFS transporter -
LUX29_RS06805 (LUX29_06805) 1392152..1393117 + 966 WP_232414305.1 rhamnan synthesis F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-78)

Antitoxin

Cro/C1-type helix-turn-helix domain

(51-105)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9182.60 Da        Isoelectric Point: 10.6133

>T228016 WP_232414299.1 NZ_CP089311:c1388706-1388458 [Aureimonas altamirensis]
MKEITYRPAAVKALRRMPTNIARRIVGKIETYASDPSSQANNVKTLQGRDGIRLRVGDWRVIMQDGEVLDVLNIGPRGGI
YD

Download         Length: 249 bp

>T228016 NZ_CP123255:2413852-2415174 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11550.99 Da        Isoelectric Point: 4.2887

>AT228016 WP_232414298.1 NZ_CP089311:c1388436-1388116 [Aureimonas altamirensis]
MVTIERTEYERLLNAADDLADIIAYDRAMAEGGESLPSEAVKRMIEGESPLRVYRDLRGLTQAQLSESAGVNRVQIADIE
AGRKSGSVDTIRKLADALSVSIDDLV

Download         Length: 321 bp

>AT228016 NZ_CP123255:2413586-2413852 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References