Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4665268..4665980 Replicon chromosome
Accession NZ_CP089309
Organism Thiocapsa bogorovii strain BBS

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LT988_RS20755 Protein ID WP_232407385.1
Coordinates 4665268..4665738 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LT988_RS20760 Protein ID WP_232407386.1
Coordinates 4665738..4665980 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT988_RS20735 (LT988_20735) 4661988..4663685 - 1698 WP_232407381.1 SulP family inorganic anion transporter -
LT988_RS20740 (LT988_20740) 4663741..4664262 - 522 WP_232407382.1 potassium channel family protein -
LT988_RS20745 (LT988_20745) 4664553..4665035 - 483 WP_269752068.1 mechanosensitive ion channel family protein -
LT988_RS20750 (LT988_20750) 4665104..4665316 + 213 WP_232407384.1 hypothetical protein -
LT988_RS20755 (LT988_20755) 4665268..4665738 - 471 WP_232407385.1 VapC toxin family PIN domain ribonuclease Toxin
LT988_RS20760 (LT988_20760) 4665738..4665980 - 243 WP_232407386.1 ribbon-helix-helix domain-containing protein Antitoxin
LT988_RS20765 (LT988_20765) 4665955..4666803 - 849 WP_232407387.1 hypothetical protein -
LT988_RS20770 (LT988_20770) 4666985..4668001 + 1017 WP_232407388.1 AraC family transcriptional regulator -
LT988_RS20775 (LT988_20775) 4668224..4669246 + 1023 WP_232407389.1 DUF1214 domain-containing protein -
LT988_RS20780 (LT988_20780) 4669341..4670840 + 1500 WP_232407390.1 DUF1254 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17460.18 Da        Isoelectric Point: 11.2269

>T228012 WP_232407385.1 NZ_CP089309:c4665738-4665268 [Thiocapsa bogorovii]
MRALLDVNVLIALLDASHMHHDTAMRWLEREQAHGWASGPITQNGCIRIMSQPAYPAPLPAAAVAARLAEAVTGPDHQFW
PDDLNPVVEKTLTCGQVLGHRQVTDAYLLALAVKNGGRFVTLRCTRGFADRLRRREGAPHRHRVKRSWMRGRMSAR

Download         Length: 471 bp

>T228012 NZ_CP123255:1119204-1119515 [Escherichia coli]
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTATACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAGATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8789.92 Da        Isoelectric Point: 6.3179

>AT228012 WP_232407386.1 NZ_CP089309:c4665980-4665738 [Thiocapsa bogorovii]
MMRTTLDIDDDVLAAAKERARLRKVSAGKMVSDLLRQALSGGTAQDETRQRGVAGFRPFDARGVIVTNDDIDTLRDREGV

Download         Length: 243 bp

>AT228012 NZ_CP123255:1119512-1119931 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGTAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCCGAGTTCGACAAAGCCGTTGCAGCAATGCCGGTT
GGCGTGGCGTTACTTCGTACGCTGATTGATCAACATAATCTGACCTACGCGGATTTGAAGAACGAAATCGGCTCTAAATC
CCTGGTCAGTCAGATTTTGTCTGGGCAACGATCCCTGACGATATCCCACATTAAGGCACTTTCAGCCCGATTTGGTGTTA
AGCCGGAATGGTTTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References