Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2317880..2318664 Replicon chromosome
Accession NZ_CP089309
Organism Thiocapsa bogorovii strain BBS

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag LT988_RS10515 Protein ID WP_232410093.1
Coordinates 2318167..2318664 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag LT988_RS10510 Protein ID WP_232410092.1
Coordinates 2317880..2318170 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT988_RS10490 (LT988_10490) 2314442..2315032 - 591 WP_232410089.1 transposase -
LT988_RS10495 (LT988_10495) 2315077..2315307 - 231 WP_232410090.1 hypothetical protein -
LT988_RS10500 (LT988_10500) 2315550..2316827 - 1278 Protein_2088 DUF1156 domain-containing protein -
LT988_RS10505 (LT988_10505) 2316864..2317676 - 813 WP_232410091.1 NYN domain-containing protein -
LT988_RS10510 (LT988_10510) 2317880..2318170 + 291 WP_232410092.1 DUF1778 domain-containing protein Antitoxin
LT988_RS10515 (LT988_10515) 2318167..2318664 + 498 WP_232410093.1 GNAT family N-acetyltransferase Toxin
LT988_RS10520 (LT988_10520) 2318755..2319321 - 567 WP_232410094.1 DUF3780 domain-containing protein -
LT988_RS10525 (LT988_10525) 2319318..2320883 - 1566 WP_232410095.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-142)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17647.27 Da        Isoelectric Point: 9.2575

>T228010 WP_232410093.1 NZ_CP089309:2318167-2318664 [Thiocapsa bogorovii]
VTLSPPSPLTGYHDCKGFSCGRKALDDWLKGRALRNQSSGASRTFVVCDQNRVIAYYALASGAVAMTAATGRLRRNMPDP
IPVVILARLAVDHSHGGRGLGRALLQDAGWRVLNAADAIGIRGLLVHAIDADARCFYHHLGFDSSPLDPATLMISLKDLR
ASLAD

Download         Length: 498 bp

>T228010 NZ_CP123255:887119-887526 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATCCACGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10838.33 Da        Isoelectric Point: 10.2779

>AT228010 WP_232410092.1 NZ_CP089309:2317880-2318170 [Thiocapsa bogorovii]
MSTAQELAAKRQTLNLRIKAEERDLIDRAARIAGKNRTEFILDASRHAAEETLLDQALLRLSPDAFAAFEARLDAPPAPN
TRLRKTMRGRPPWDTE

Download         Length: 291 bp

>AT228010 NZ_CP123255:886872-887138 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAACCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References