Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/DUF433(antitoxin) |
| Location | 1728761..1729335 | Replicon | chromosome |
| Accession | NZ_CP089309 | ||
| Organism | Thiocapsa bogorovii strain BBS | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LT988_RS07875 | Protein ID | WP_232409625.1 |
| Coordinates | 1728761..1729108 (-) | Length | 116 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | LT988_RS07880 | Protein ID | WP_232409626.1 |
| Coordinates | 1729105..1729335 (-) | Length | 77 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LT988_RS07845 (LT988_07845) | 1724928..1726364 | - | 1437 | WP_232409621.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| LT988_RS07850 (LT988_07850) | 1726546..1727238 | + | 693 | WP_232409622.1 | hypothetical protein | - |
| LT988_RS07855 (LT988_07855) | 1727255..1727491 | + | 237 | WP_232409623.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| LT988_RS07860 (LT988_07860) | 1727657..1728094 | - | 438 | WP_232409624.1 | DUF29 domain-containing protein | - |
| LT988_RS07865 (LT988_07865) | 1728215..1728346 | - | 132 | WP_232410533.1 | helix-turn-helix domain-containing protein | - |
| LT988_RS07870 (LT988_07870) | 1728421..1728735 | - | 315 | Protein_1562 | transposase | - |
| LT988_RS07875 (LT988_07875) | 1728761..1729108 | - | 348 | WP_232409625.1 | DUF5615 family PIN-like protein | Toxin |
| LT988_RS07880 (LT988_07880) | 1729105..1729335 | - | 231 | WP_232409626.1 | DUF433 domain-containing protein | Antitoxin |
| LT988_RS07885 (LT988_07885) | 1729669..1729854 | - | 186 | WP_232409627.1 | hypothetical protein | - |
| LT988_RS07890 (LT988_07890) | 1730239..1730487 | + | 249 | WP_232409628.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| LT988_RS07895 (LT988_07895) | 1730484..1730903 | + | 420 | WP_232409629.1 | PIN domain-containing protein | - |
| LT988_RS07900 (LT988_07900) | 1731170..1731376 | + | 207 | WP_232409630.1 | hypothetical protein | - |
| LT988_RS07905 (LT988_07905) | 1731373..1731627 | + | 255 | WP_232409631.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LT988_RS07910 (LT988_07910) | 1732251..1733294 | - | 1044 | WP_232409632.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1723838..1745119 | 21281 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 116 a.a. Molecular weight: 12709.66 Da Isoelectric Point: 4.3721
>T228009 WP_232409625.1 NZ_CP089309:c1729108-1728761 [Thiocapsa bogorovii]
VTIWLDAQLPPTLAAWLASTFEIRCLAVRDLGLRDSDDRAIFQAARDQGDVVIMSKDSDFVELALRLGPPPRILWLTCGN
VTNSHPRRILTEVLPDAMAMLEVGEVVVEIGDRNA
VTIWLDAQLPPTLAAWLASTFEIRCLAVRDLGLRDSDDRAIFQAARDQGDVVIMSKDSDFVELALRLGPPPRILWLTCGN
VTNSHPRRILTEVLPDAMAMLEVGEVVVEIGDRNA
Download Length: 348 bp
>T228009 NZ_CP123255:c751543-751166 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCAGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGTTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCAGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8510.93 Da Isoelectric Point: 4.5720
>AT228009 WP_232409626.1 NZ_CP089309:c1729335-1729105 [Thiocapsa bogorovii]
MDKHLVRDRITTNPDQCGGRPCIRGMRIRVVDILEMLAEGVSAREILADFPDLEPEDIQACLLLAAERVDIPRLVA
MDKHLVRDRITTNPDQCGGRPCIRGMRIRVVDILEMLAEGVSAREILADFPDLEPEDIQACLLLAAERVDIPRLVA
Download Length: 231 bp
>AT228009 NZ_CP123255:c751964-751590 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|