Detailed information of TA system TA228003

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapC-vagC/VapC-VagC
• Location: 469230..469873
• Replicon: chromosome
• Accession: NZ_CP089309
• Organism: Thiocapsa bogorovii strain BBS

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: LT988_RS02215
• Protein ID: WP_232408640.1
• Coordinates: 469466..469873 (+)
• Length: 136 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: LT988_RS02210
• Protein ID: WP_232408639.1
• Coordinates: 469230..469466 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LT988_RS02175 (LT988_02175)	465293..465841	+	549	WP_232408633.1	hypothetical protein	-
LT988_RS02180 (LT988_02180)	465977..466327	+	351	WP_232408634.1	helix-turn-helix domain-containing protein	-
LT988_RS02185 (LT988_02185)	466620..467516	+	897	WP_232408635.1	HipA domain-containing protein	-
LT988_RS02190 (LT988_02190)	467588..467794	-	207	WP_232408636.1	hypothetical protein	-
LT988_RS02195 (LT988_02195)	468042..468329	+	288	Protein_437	glycosyltransferase	-
LT988_RS02200 (LT988_02200)	468347..468574	+	228	WP_232408637.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LT988_RS02205 (LT988_02205)	468587..468946	+	360	WP_232408638.1	HigA family addiction module antitoxin	-
LT988_RS02210 (LT988_02210)	469230..469466	+	237	WP_232408639.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
LT988_RS02215 (LT988_02215)	469466..469873	+	408	WP_232408640.1	type II toxin-antitoxin system VapC family toxin	Toxin
LT988_RS02220 (LT988_02220)	469984..470236	+	253	Protein_442	transposase	-
LT988_RS02225 (LT988_02225)	470391..471041	+	651	WP_232408641.1	hypothetical protein	-
LT988_RS02230 (LT988_02230)	471114..471419	+	306	WP_232408642.1	transposase	-
LT988_RS02235 (LT988_02235)	471543..471953	+	411	WP_232408643.1	hypothetical protein	-
LT988_RS02240 (LT988_02240)	471960..472487	+	528	WP_232408644.1	hypothetical protein	-
LT988_RS02245 (LT988_02245)	472589..473080	+	492	WP_232408645.1	hypothetical protein	-
LT988_RS02250 (LT988_02250)	473277..473717	-	441	WP_232408646.1	type II toxin-antitoxin system VapC family toxin	-
LT988_RS02255 (LT988_02255)	473704..474330	-	627	WP_232408647.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-117)

Antitoxin

• SpoVT-AbrB domain (7-44)

Sequences

Toxin

Protein

• Length: 136 a.a.
• Molecular weight: 14954.21 Da
• Isoelectric Point: 6.4745

>T228003 WP_232408640.1 NZ_CP089309:469466-469873 [Thiocapsa bogorovii]
MPRYMLDTNMCVYLIKHQPEIVARRFAQCHVGDVVMSAITFAELEYGVAVAAHPETERGYLDSLIQDIPVAPFDVAAGRA
YASVRLATRDSRKNALDKLIAAHAQSLNVTLVTNNTKDFAGYPGVMIENWLMPNT

Nucleotide

• Length: 408 bp

>T228003 NZ_CP123252:75516-75848 [Providencia rettgeri]
ATGGTATCTCGATACGTTCCTGATTCTGGCGATTTGATTTGGATTGACTTTGATCCAGTTGAAGGACATGAGCAGGGCGG
TCATCGTCCAGCAGTTGTCCTCAGCCCATTTGCATACAATAATAAAGTAGGGCTCTTATTATGCGTACCATGTACAACTA
AGGGCAAAGGCTATCCATTTGAATGCGAACTCTCGAACGAAAGAGACAGCTACGCATTAGCGGATCAAGTTACATGTGTT
GACTGGAGAGCTCGTAAGGTTACTAAAAAGGGCAAAGTGGAGGCATCAGAACTGGCAGAGATAAAAGCTAAAGCAAAGGC
GTTAATAGGTTAG

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8977.24 Da
• Isoelectric Point: 8.0292

>AT228003 WP_232408639.1 NZ_CP089309:469230-469466 [Thiocapsa bogorovii]
MRITKAFKNGHSQAVRIPAELAFERMDIELEIERCGDELRIRPARRSLAGVLTKFARFSPDFMADGRGEQEQDGRDRL

Nucleotide

• Length: 237 bp

>AT228003 NZ_CP123252:75271-75516 [Providencia rettgeri]
ATGGCTCAGGTCACAGTAAAAAAATGGGGCAATAGCCCGTCTGTACGGCTTCCTGTTGCAATCATGCAAAAAGCGGCACT
TAGCGTTGATGATACGGTTGAAATAGCGGTAGAAGAAGGTCGTATCATCATTACGCCAGTTAAAGCAGTAGAATACTCAT
TAGAAAATTTGTTAGCCGGTATCACGCCGGAGAATATTCATGAGAAAGTAGACTTCGGAGCTCGAACAGGTAAGGAATTA
ATTTAA