228002

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 436959..437523 Replicon chromosome
Accession NZ_CP089309
Organism Thiocapsa bogorovii strain BBS

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag LT988_RS02020 Protein ID WP_232408608.1
Coordinates 437167..437523 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag LT988_RS02015 Protein ID WP_120798107.1
Coordinates 436959..437183 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT988_RS01990 (LT988_01990) 432448..432993 - 546 WP_232408603.1 DUF3782 domain-containing protein -
LT988_RS01995 (LT988_01995) 433129..434208 - 1080 WP_232408604.1 hypothetical protein -
LT988_RS02000 (LT988_02000) 434294..434995 + 702 WP_232408605.1 S24 family peptidase -
LT988_RS02005 (LT988_02005) 435098..435556 + 459 WP_232408606.1 DUF1640 domain-containing protein -
LT988_RS02010 (LT988_02010) 436572..436820 + 249 WP_232408607.1 hypothetical protein -
LT988_RS02015 (LT988_02015) 436959..437183 + 225 WP_120798107.1 DUF6290 family protein Antitoxin
LT988_RS02020 (LT988_02020) 437167..437523 + 357 WP_232408608.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LT988_RS02025 (LT988_02025) 437507..437743 + 237 WP_232408609.1 DUF433 domain-containing protein -
LT988_RS02030 (LT988_02030) 438545..439456 + 912 WP_232408610.1 Rpn family recombination-promoting nuclease/putative transposase -
LT988_RS02035 (LT988_02035) 440105..440404 - 300 WP_232408611.1 BrnA antitoxin family protein -
LT988_RS02040 (LT988_02040) 440496..440663 - 168 WP_232408612.1 BrnT family toxin -
LT988_RS02045 (LT988_02045) 440679..441005 + 327 WP_232408613.1 PD-(D/E)XK nuclease family transposase -
LT988_RS02050 (LT988_02050) 441139..441303 + 165 WP_232408614.1 hypothetical protein -
LT988_RS02055 (LT988_02055) 441523..441729 + 207 WP_232408615.1 type II toxin-antitoxin system RelE/ParE family toxin -
LT988_RS02060 (LT988_02060) 441840..442373 + 534 WP_232408616.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13475.42 Da        Isoelectric Point: 8.1029

>T228002 WP_232408608.1 NZ_CP089309:437167-437523 [Thiocapsa bogorovii]
MAWTIEFDPAAERELGKLDPPIARRILAFLHGRVAPLDDPRHLGEALKGSRLGDLWKYRVGDYRLIVSIEDDTVRLLVVR
LGHRRDVYRRSVTPRAWQINLSPFGANPCDEASHEHGI

Download         Length: 357 bp

>T228002 NZ_CP123251:c4534124-4532805 [Providencia rettgeri]
ATGGCGACTTTGCATGTATACATGAATGGTTACTTAGTTGGGGATTTGATTCGTTCAAGTACTGGTGCTCACCAATTTAC
TTATAATAGTCACTGGTTGGAAACATCAGGTGCTCGACCTATTTCTTTATCAATGCCACTTAGGCACCAAGAATATCGAG
GAGACGAAGTTTATAATTTTTTTGATAATCTCCTACCGGACAATATTGAGATACGGAATCGAATTGTTAGTCGTTATCAA
GCGGATTCAAATCAACCTTTCGATTTATTATCTAAGATTGGCCAGGATAGTGTGGGGGCTTTACAACTCATTCTAGATGG
GCAAAGAGTCAGTAATATCAGAAAAATTGAATATAAACCCTTATCTAATAAGCAACTAGAAAAAATATTAACAGGGTATA
AAGCGAATGCTCCTTTAGGCATGATTGAAGATGAAGATGACTTTAGGATCTCACTTGCGGGCGCTCAAGAGAAAACCGCA
TTACTCTATTTAGATGGGCATTGGTGCTTACCTCAGAATGCGACTCCAACTACCCATATTATTAAACTTCCCATTGGTAA
AATAGAAAGCCATTCTTATTCGATAGATATGTCGGATAGTGTAGAAAATGAATATTTATGTTTATTGATAGCAAAAGAGT
TTGGCCTAGATGTGCCTCGTAGCTTTATTTTAAATGTAGGTGAAATAAAGGCGTTAGCGGTTGAACGTTTTGACCGTAAA
TATTCTTCTGATTCCTCGTGGATTATGCGTTTACCACAAGAAGATTTTTGTCAAACATTGAATATTTCACCAGCAAGAAA
ATATCAAAATCATGGTGGACCGGGTATTTCTGAAATTATGAATTACTTATTGGGTTCAATAAATGCAGAGAAAGATAGAT
ATCAGTTTATGAAGAGCCAAGTTTTGTTCTGGCTACTTGCAGCGACGGATGGTCATGCTAAAAATTTTTCATTATTTATT
GAACCTGAAGGCCGTTATCAGTTAACACCTTTTTACGATATTTTGTCCATGTATCCTAGTTATGGGGGGAGGGGAATTAA
CCCTAGAGATGCCAAATTGGCTATGGGGCTGAAGGGAACAAGGGGGATGAAATACAATATAGAGCAAATTTTCCCAAGAC
ATTTTTTTTCAACGGCCAAAGCCGTTGGATTTGATCGTGCTGAGATGGAAAAAATCTTAATTGAATTTGGTGAGCAAATG
GAAAGTGTTATTAAGAAAGTGAGAGAACAATTACCCACAGATTTCCCTGAGCATATCGCAGACTCAATTCTATCCGGATT
ACATCACAAAGCAGCGAGATTAAATAAAGGCTGGGACTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8488.68 Da        Isoelectric Point: 4.4550

>AT228002 WP_120798107.1 NZ_CP089309:436959-437183 [Thiocapsa bogorovii]
MLAIRLPADVEQRLEALARATGRTKTFYAREAILEHLDDLEDVYLAEQRLIDIRAGKTQTVPLDELMTRYGLDD

Download         Length: 225 bp

>AT228002 NZ_CP123251:c4534381-4534124 [Providencia rettgeri]
ATGAAAGTGACGAATACCCGACAACTTAGTGCTTATATGAAGGATGTCAGAGAGACGAAAAAGTTATCTCAAAGCAAAGT
CGCTAGTAAAGTAGGTATTCGGCAAGATACTGTTTCTAGCTTTGAACTCTCTCCTGACTCTACCAAATTAGAAACCTTTT
TTAAGATTTTATCTGCCCTCAATTTAGAACTCGATATTAAACCGCGAAATGAAAGCGGCTCATCAAATTCAGACTCCGGA
TGGAAGGAGGAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References