Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 3300277..3300863 Replicon chromosome
Accession NZ_CP089304
Organism Pseudomonas sp. NIBR-H-19

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LS633_RS15225 Protein ID WP_095035893.1
Coordinates 3300555..3300863 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LS633_RS15220 Protein ID WP_146425889.1
Coordinates 3300277..3300558 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LS633_RS15190 (LS633_15190) 3295925..3296287 + 363 WP_095035886.1 hypothetical protein -
LS633_RS15195 (LS633_15195) 3296510..3297523 + 1014 WP_095035887.1 DNA adenine methylase -
LS633_RS15200 (LS633_15200) 3297583..3297945 + 363 WP_141232571.1 hypothetical protein -
LS633_RS15205 (LS633_15205) 3298079..3298510 + 432 WP_232391459.1 hypothetical protein -
LS633_RS15210 (LS633_15210) 3298606..3299208 + 603 WP_232391460.1 hypothetical protein -
LS633_RS15215 (LS633_15215) 3299409..3300242 + 834 WP_232391461.1 hypothetical protein -
LS633_RS15220 (LS633_15220) 3300277..3300558 - 282 WP_146425889.1 putative addiction module antidote protein Antitoxin
LS633_RS15225 (LS633_15225) 3300555..3300863 - 309 WP_095035893.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LS633_RS15230 (LS633_15230) 3300919..3301266 - 348 WP_232391462.1 hypothetical protein -
LS633_RS15235 (LS633_15235) 3301412..3302119 - 708 WP_232391463.1 hypothetical protein -
LS633_RS15240 (LS633_15240) 3302280..3302996 - 717 WP_120266248.1 hypothetical protein -
LS633_RS15245 (LS633_15245) 3303131..3304597 + 1467 WP_162939346.1 hypothetical protein -
LS633_RS15250 (LS633_15250) 3304594..3305310 + 717 WP_120266246.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3277523..3344205 66682


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11636.41 Da        Isoelectric Point: 9.0591

>T227996 WP_095035893.1 NZ_CP089304:c3300863-3300555 [Pseudomonas sp. NIBR-H-19]
MNTLIRTHEFDAWLKGLKDVQARLRIISRIMSAQEGNFGDCEPVGEGISEMRIFVGPGYRVYYTRRGEVVYLLLCGGNKS
SQKRDIKLAKSILDEIEQGDRK

Download         Length: 309 bp

>T227996 NZ_CP123251:2425651-2426109 [Providencia rettgeri]
ATGATTTTATATCGATTGGTTAAATCCAATTTTGCGCATGATGCATGGTCGGGCCAAGGAGCTATGCTCTACGGCGGGCG
TTGGAATCATAAAGGGACTCCTGCTGTTTATACTTCAACAAGTATTTCATTAGCGACCCTTGAAATACTCGTTCACATCA
ATCAAGACAGACTATTGAACCAGTTCAGCTTACTATCCATAGATATCAATGATAAGTACGTGATGAAATTGTCGTTAGAT
CACCTTCCGACAGATTGGCAACAAGACCCCGCACCAACCTCCACCATGGATATTGGCACTATATGGCTTAATAACCAAGA
TAGTCTAGCATTATTAATTCCCTCTTGTATTGTTCCCTATGAATACAACGCAATTATTAACCCGTTACATCCGCAATTTC
AAAAAGCTTTACATACCGTTAAACCACTAGATTTTAGTGTTGACCCGCGCTTAGCATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10329.86 Da        Isoelectric Point: 5.8373

>AT227996 WP_146425889.1 NZ_CP089304:c3300558-3300277 [Pseudomonas sp. NIBR-H-19]
MRELKVFEASDYLNNEDEIAQFLTISLEDPNPDVFLRALQEVAKARGMSQLAKDAGINRESLYKALAPGAKPRYDTVLKL
VNALGVKLTAQHV

Download         Length: 282 bp

>AT227996 NZ_CP123251:2425193-2425654 [Providencia rettgeri]
ATGAGAAACTATATCCCCACAACCCCACTTCAACCGACTGCTTCATCCTTTAAACCACTGTGGCGCCATGTAGGGTTACC
CGCAGAACGTGGTATTGAGTTAACTCATTTCTTGCGTCAAGGCCTATCTGTCTCTGTCTTAGACAATATCCAAGAATGGT
CAGGAATGAGCAAAACTGAATTATTGCGAATATCCGGCATTAATGAGCGCAATATTGCTCGACGTAAAAATGCTGGCCAG
CCCCTTAATGCTGATGAAAGTGAGAGAATTGCTCGTCTAGTGCGGGTATTCGATGCTGCGGTGCGTTTATTTAATGGAGA
TAAGCACGCGGCAAGTGATTGGCTTAACCACCCAGTTAAAGGGTTAGGACATTTACGCCCTATTGAGCTTATTGCGACAG
AAAGCGGAGCCATTGAAGTGATTGATTTGATTGGCCGTATTGAACATGGCGTATTCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References