Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2377323..2377839 Replicon chromosome
Accession NZ_CP089304
Organism Pseudomonas sp. NIBR-H-19

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LS633_RS11090 Protein ID WP_210702758.1
Coordinates 2377558..2377839 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LS633_RS11085 Protein ID WP_150603970.1
Coordinates 2377323..2377568 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LS633_RS11060 (LS633_11060) 2372592..2373659 + 1068 WP_210702756.1 HlyD family secretion protein -
LS633_RS11065 (LS633_11065) 2373656..2375206 + 1551 WP_232392696.1 efflux transporter outer membrane subunit -
LS633_RS11070 (LS633_11070) 2375260..2376021 - 762 WP_210703091.1 slipin family protein -
LS633_RS11075 (LS633_11075) 2376021..2376551 - 531 WP_232392697.1 NfeD family protein -
LS633_RS11080 (LS633_11080) 2376985..2377230 + 246 WP_047299243.1 DUF2789 domain-containing protein -
LS633_RS11085 (LS633_11085) 2377323..2377568 + 246 WP_150603970.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LS633_RS11090 (LS633_11090) 2377558..2377839 + 282 WP_210702758.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LS633_RS11095 (LS633_11095) 2377984..2378412 + 429 WP_042557041.1 winged helix DNA-binding protein -
LS633_RS11100 (LS633_11100) 2378409..2380472 + 2064 WP_210702759.1 FUSC family protein -
LS633_RS11105 (LS633_11105) 2380469..2380678 + 210 WP_007917703.1 DUF1656 domain-containing protein -
LS633_RS11110 (LS633_11110) 2380675..2381562 + 888 WP_047299245.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10891.86 Da        Isoelectric Point: 10.5399

>T227995 WP_210702758.1 NZ_CP089304:2377558-2377839 [Pseudomonas sp. NIBR-H-19]
MTYKLEFLPSAHKEWNKLGHTLRDQFKKKLAERLMLPRVLADALHGMTDCYKIKLKASGYRLVYQVIEERVVVSVVAVGK
RERSNVYENAKKR

Download         Length: 282 bp

>T227995 NZ_CP123251:c1771783-1771598 [Providencia rettgeri]
GTGCAAAGTTCGGAACTGATAAACATACTGCAAAAAAACGGTTGGAAACTTGAAAGAATAAGAGGAAGTCACCATCAGTT
TTCCCACCCACATTTTTCAATTGTAATTACTGTTCCGCATCCACAAAAAGATTTAAAGATAGGCACACTAAATCACATTT
TGAAGGCTGCGAAACTAAAACATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8746.04 Da        Isoelectric Point: 4.4988

>AT227995 WP_150603970.1 NZ_CP089304:2377323-2377568 [Pseudomonas sp. NIBR-H-19]
MQNVLADMAVSVSELKKNPSAVLSGAHGGAVAVLNHNRVMGYMVPADVYEAMMERLDDLELAEIVRARSHETPVPVSLDD
L

Download         Length: 246 bp

>AT227995 NZ_CP123251:c1771548-1771135 [Providencia rettgeri]
ATGCTTTATACCGCCTTTATTGAAATTGATAATGATGGCAGCGCAAGTGGCTGGTTTCCTGATATTGAAGGATGTACATT
CGCGGGCAGCAATATAGAAGAGGCTTACGCAGAAGCAAAATCAGCAATTGATGCTCATTTTGAATTATTGAGTGAAAAAG
GCTTTGAGATCCCATTATCGAAATCTCAGCAAACGCTATTGAACCCAATACAACCTGAATATGCGCATGGGATATGGTTA
TTTGTGGATGTCGATATGGATAAATACGATGGCCGTACTGAGCGTATTAATATCACCTTGCCGCATCGTTTATTACATCG
TATTGATGCTTTAGTGAAGGTTAATCCTGAATATGGTAGCCGTAGTGGTTTTATTGCTGTTGCAGCTCGTAAAGAATTAA
AAAAAACCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References