Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 949693..950198 Replicon chromosome
Accession NZ_CP089304
Organism Pseudomonas sp. NIBR-H-19

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LS633_RS04530 Protein ID WP_210706146.1
Coordinates 949944..950198 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LS633_RS04525 Protein ID WP_150604324.1
Coordinates 949693..949947 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LS633_RS04505 (LS633_04505) 944743..946140 + 1398 WP_232392508.1 replication endonuclease -
LS633_RS04510 (LS633_04510) 946258..947610 - 1353 WP_232392509.1 MobV family relaxase -
LS633_RS04515 (LS633_04515) 947607..948083 - 477 WP_232392510.1 hypothetical protein -
LS633_RS04520 (LS633_04520) 948160..949461 + 1302 Protein_888 alkaline phosphatase D family protein -
LS633_RS04525 (LS633_04525) 949693..949947 + 255 WP_150604324.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LS633_RS04530 (LS633_04530) 949944..950198 + 255 WP_210706146.1 Txe/YoeB family addiction module toxin Toxin
LS633_RS04535 (LS633_04535) 950195..951379 - 1185 WP_210706147.1 aspartate aminotransferase family protein -
LS633_RS04540 (LS633_04540) 951482..952387 + 906 WP_115147738.1 LysR family transcriptional regulator -
LS633_RS04545 (LS633_04545) 952528..953232 + 705 WP_210706148.1 hypothetical protein -
LS633_RS04550 (LS633_04550) 953303..953794 - 492 WP_232392511.1 RidA family protein -
LS633_RS04555 (LS633_04555) 954128..955015 - 888 WP_210706149.1 heme o synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10030.67 Da        Isoelectric Point: 9.8070

>T227993 WP_210706146.1 NZ_CP089304:949944-950198 [Pseudomonas sp. NIBR-H-19]
MKIEFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGVGKPEPLKHNMSGLWSRRITAEHRLVYKIDKGEICVFTC
RYQY

Download         Length: 255 bp

>T227993 NZ_CP123251:c884920-884717 [Providencia rettgeri]
ATGACCAAATCTGATTATCTGATGCGTTTAAGAAAATGCACCACAATTGAAACACTTGAGCGTGTCATTGAAAAAAATAA
GTATGAATTATCTGATGATGAGCTAGAGCTATTCTATTCAGCAGCAGATCACCGCTTAGCTGAACTCACAATGAATAAGC
TTTATGATAAAATCCCAGCGTCTGTTTGGAAGTTTGTTAGATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9501.84 Da        Isoelectric Point: 5.1442

>AT227993 WP_150604324.1 NZ_CP089304:949693-949947 [Pseudomonas sp. NIBR-H-19]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEERAGKAQVRQ
LIEE

Download         Length: 255 bp

>AT227993 NZ_CP123251:c885363-884995 [Providencia rettgeri]
ATGGATGAATACTCACCCAAAAGACATGATATAGCAGAACTAAAATACTTATGTAATAGTCTCAATAGAGACGCTATTTT
AAGCTTACAAAAAACAAATACACACTGGATTAATGATTTAAGCTCCCCGCAAAGCGCAGCCTTGAATGAACTCATTGAAC
ATATCGCTGCATTTGTATGGCGGTTTAAAATCAAATACCCAAAAGAAAATCTTGTTATATCACTTATCGAAGAATACCTC
GATGAGACCTATGATTTATTCGGCAGCCCAGTTATCACACTTAGTGAAATTATAGACTGGGAAGCAATGAATCACAGCCT
TGTCGCTGTGCTGGATGATGACCTAAAGTGCCTAACCAGCAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References