Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 290619..291574 Replicon chromosome
Accession NZ_CP089238
Organism Pseudomonas aeruginosa strain JNQH-PA033

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag LSG45_RS01375 Protein ID WP_170868726.1
Coordinates 291248..291574 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag LSG45_RS01370 Protein ID WP_023107584.1
Coordinates 290619..291176 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSG45_RS01345 (LSG45_01345) 285651..285938 - 288 WP_234575336.1 hypothetical protein -
LSG45_RS01350 (LSG45_01350) 286030..286506 - 477 WP_234575337.1 MarR family transcriptional regulator -
LSG45_RS01355 (LSG45_01355) 286547..288037 - 1491 WP_234575338.1 UbiD family decarboxylase HudA -
LSG45_RS01360 (LSG45_01360) 288159..288845 - 687 WP_003106170.1 YoaK family protein -
LSG45_RS01365 (LSG45_01365) 289037..289969 - 933 WP_003084116.1 hypothetical protein -
LSG45_RS01370 (LSG45_01370) 290619..291176 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
LSG45_RS01375 (LSG45_01375) 291248..291574 + 327 WP_170868726.1 hypothetical protein Toxin
LSG45_RS01385 (LSG45_01385) 293019..294461 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12366.33 Da        Isoelectric Point: 8.6957

>T227905 WP_170868726.1 NZ_CP089238:291248-291574 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

>T227905 NZ_CP123231:1898675-1898929 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT227905 WP_023107584.1 NZ_CP089238:290619-291176 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp

>AT227905 NZ_CP123231:1898427-1898678 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References