Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2040287..2041534 | Replicon | chromosome |
| Accession | NC_010552 | ||
| Organism | Burkholderia ambifaria MC40-6 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | B1YZ45 |
| Locus tag | BAMMC406_RS24555 | Protein ID | WP_012366624.1 |
| Coordinates | 2040953..2041534 (+) | Length | 194 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | BAMMC406_RS24550 | Protein ID | WP_012366623.1 |
| Coordinates | 2040287..2040844 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BAMMC406_RS24530 | 2036170..2036805 | + | 636 | WP_012366619.1 | cysteine hydrolase | - |
| BAMMC406_RS24535 | 2036889..2037620 | - | 732 | WP_012366620.1 | ribonuclease T2 | - |
| BAMMC406_RS24540 | 2037802..2039205 | - | 1404 | WP_012366621.1 | hypothetical protein | - |
| BAMMC406_RS24545 | 2039568..2040215 | + | 648 | WP_012366622.1 | hypothetical protein | - |
| BAMMC406_RS24550 | 2040287..2040844 | + | 558 | WP_012366623.1 | helix-turn-helix domain-containing protein | Antitoxin |
| BAMMC406_RS24555 | 2040953..2041534 | + | 582 | WP_012366624.1 | HD domain-containing protein | Toxin |
| BAMMC406_RS24560 | 2041593..2042321 | + | 729 | WP_012366625.1 | class I SAM-dependent methyltransferase | - |
| BAMMC406_RS24565 | 2042616..2043368 | + | 753 | WP_012366626.1 | hypothetical protein | - |
| BAMMC406_RS24570 | 2043413..2044951 | - | 1539 | WP_012366627.1 | MFS transporter | - |
| BAMMC406_RS24575 | 2045129..2046063 | + | 935 | Protein_1801 | LysR family transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 194 a.a. Molecular weight: 21441.95 Da Isoelectric Point: 4.8564
>T22790 WP_012366624.1 NC_010552:2040953-2041534 [Burkholderia ambifaria MC40-6]
MNLDTIHARLDFLREAERLKDVLRSGHTSTGRRESTAEHSWRLCLMALVFADALPDVDTTKLLKLCVVHDLGEALHGDVP
AIEQAAHPDKSTHERDDLLTLTAGLDRALRDEIVALWDEYEAAESPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRYTDATPLFGAIRAIVDADTQRRIDARGGDA
MNLDTIHARLDFLREAERLKDVLRSGHTSTGRRESTAEHSWRLCLMALVFADALPDVDTTKLLKLCVVHDLGEALHGDVP
AIEQAAHPDKSTHERDDLLTLTAGLDRALRDEIVALWDEYEAAESPEARAAKALDKLETILQHNQGSNPPDFDYAFNLGY
GRRYTDATPLFGAIRAIVDADTQRRIDARGGDA
Download Length: 582 bp
>T22790 NC_010552:2040953-2041534 [Burkholderia ambifaria MC40-6]
ATGAACCTCGACACGATCCACGCGCGGCTCGATTTCCTGCGCGAAGCCGAACGCCTGAAAGACGTGCTGCGCAGCGGCCA
TACGTCGACGGGCCGCCGCGAAAGCACCGCCGAGCACAGCTGGCGTCTCTGCCTGATGGCGCTCGTGTTCGCCGATGCGC
TGCCCGACGTCGACACGACGAAGCTGCTGAAACTGTGCGTCGTCCACGATCTCGGCGAAGCGCTGCACGGCGACGTCCCC
GCGATCGAGCAGGCCGCGCATCCGGACAAGAGCACGCACGAACGCGACGACCTGCTGACGCTGACGGCCGGCCTCGATCG
CGCGCTGCGCGACGAGATCGTCGCGCTGTGGGATGAATACGAGGCGGCCGAATCACCGGAAGCGCGCGCCGCGAAGGCGC
TCGACAAGCTCGAGACGATTCTGCAGCACAACCAGGGCAGCAATCCGCCCGACTTCGACTACGCGTTCAATCTCGGCTAC
GGCCGGCGCTACACCGACGCGACGCCGCTGTTCGGCGCGATCCGCGCGATCGTCGACGCGGACACGCAACGCCGGATCGA
CGCACGCGGCGGCGACGCGTAA
ATGAACCTCGACACGATCCACGCGCGGCTCGATTTCCTGCGCGAAGCCGAACGCCTGAAAGACGTGCTGCGCAGCGGCCA
TACGTCGACGGGCCGCCGCGAAAGCACCGCCGAGCACAGCTGGCGTCTCTGCCTGATGGCGCTCGTGTTCGCCGATGCGC
TGCCCGACGTCGACACGACGAAGCTGCTGAAACTGTGCGTCGTCCACGATCTCGGCGAAGCGCTGCACGGCGACGTCCCC
GCGATCGAGCAGGCCGCGCATCCGGACAAGAGCACGCACGAACGCGACGACCTGCTGACGCTGACGGCCGGCCTCGATCG
CGCGCTGCGCGACGAGATCGTCGCGCTGTGGGATGAATACGAGGCGGCCGAATCACCGGAAGCGCGCGCCGCGAAGGCGC
TCGACAAGCTCGAGACGATTCTGCAGCACAACCAGGGCAGCAATCCGCCCGACTTCGACTACGCGTTCAATCTCGGCTAC
GGCCGGCGCTACACCGACGCGACGCCGCTGTTCGGCGCGATCCGCGCGATCGTCGACGCGGACACGCAACGCCGGATCGA
CGCACGCGGCGGCGACGCGTAA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20226.20 Da Isoelectric Point: 11.0874
>AT22790 WP_012366623.1 NC_010552:2040287-2040844 [Burkholderia ambifaria MC40-6]
MTTSPLHTPPLGPQLKRWRALRRVKQSHAAELFGVAQSTISRWEAGIQQMSPDERATAERLLAARLDSAGDHALARLIAS
STARMHLVCDLTHRLLACSPSRAAEFSRPLPALLGTSLWRYASPEIVRMEAALDPLGWHDRAGPPSVEFATGTNASRVVP
IRGSTCRWTRMTLSDGSAARLVETL
MTTSPLHTPPLGPQLKRWRALRRVKQSHAAELFGVAQSTISRWEAGIQQMSPDERATAERLLAARLDSAGDHALARLIAS
STARMHLVCDLTHRLLACSPSRAAEFSRPLPALLGTSLWRYASPEIVRMEAALDPLGWHDRAGPPSVEFATGTNASRVVP
IRGSTCRWTRMTLSDGSAARLVETL
Download Length: 558 bp
>AT22790 NC_010552:2040287-2040844 [Burkholderia ambifaria MC40-6]
ATGACGACCTCGCCGCTTCACACCCCGCCGCTCGGCCCGCAACTCAAGCGCTGGCGCGCGCTGCGCCGCGTGAAGCAGAG
CCATGCGGCCGAGCTGTTCGGCGTCGCGCAATCGACGATCTCGCGCTGGGAAGCCGGCATCCAGCAGATGTCGCCCGACG
AGCGCGCGACGGCCGAGCGGCTGCTTGCCGCGCGTCTCGATTCGGCCGGCGACCACGCGCTCGCGCGGCTGATCGCCAGC
AGCACGGCCCGCATGCATCTCGTGTGCGACCTCACGCATCGGCTGCTCGCCTGCTCGCCATCGCGCGCGGCCGAGTTCTC
GCGGCCGCTGCCGGCGTTGCTCGGTACCTCGCTATGGCGCTATGCATCGCCGGAAATCGTCCGCATGGAAGCCGCGCTCG
ACCCGCTCGGCTGGCACGATCGCGCGGGGCCGCCGAGCGTCGAGTTCGCGACCGGCACCAATGCGTCGCGCGTCGTGCCG
ATCCGTGGCAGTACCTGCCGGTGGACGCGCATGACGCTGTCGGACGGCTCGGCCGCGCGGCTCGTCGAAACGCTGTAG
ATGACGACCTCGCCGCTTCACACCCCGCCGCTCGGCCCGCAACTCAAGCGCTGGCGCGCGCTGCGCCGCGTGAAGCAGAG
CCATGCGGCCGAGCTGTTCGGCGTCGCGCAATCGACGATCTCGCGCTGGGAAGCCGGCATCCAGCAGATGTCGCCCGACG
AGCGCGCGACGGCCGAGCGGCTGCTTGCCGCGCGTCTCGATTCGGCCGGCGACCACGCGCTCGCGCGGCTGATCGCCAGC
AGCACGGCCCGCATGCATCTCGTGTGCGACCTCACGCATCGGCTGCTCGCCTGCTCGCCATCGCGCGCGGCCGAGTTCTC
GCGGCCGCTGCCGGCGTTGCTCGGTACCTCGCTATGGCGCTATGCATCGCCGGAAATCGTCCGCATGGAAGCCGCGCTCG
ACCCGCTCGGCTGGCACGATCGCGCGGGGCCGCCGAGCGTCGAGTTCGCGACCGGCACCAATGCGTCGCGCGTCGTGCCG
ATCCGTGGCAGTACCTGCCGGTGGACGCGCATGACGCTGTCGGACGGCTCGGCCGCGCGGCTCGTCGAAACGCTGTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|