Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 627957..628577 Replicon chromosome
Accession NC_010552
Organism Burkholderia ambifaria MC40-6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BAMMC406_RS18480 Protein ID WP_012365544.1
Coordinates 628260..628577 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BAMMC406_RS18475 Protein ID WP_012365543.1
Coordinates 627957..628256 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAMMC406_RS18450 623113..624402 + 1290 WP_012365539.1 Rieske 2Fe-2S domain-containing protein -
BAMMC406_RS18455 624399..624887 + 489 WP_011660415.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
BAMMC406_RS18460 624904..625230 + 327 WP_012365540.1 non-heme iron oxygenase ferredoxin subunit -
BAMMC406_RS18465 625220..626440 + 1221 WP_012365541.1 FAD-dependent oxidoreductase -
BAMMC406_RS18470 626628..627914 + 1287 WP_012365542.1 DUF445 domain-containing protein -
BAMMC406_RS18475 627957..628256 - 300 WP_012365543.1 putative addiction module antidote protein Antitoxin
BAMMC406_RS18480 628260..628577 - 318 WP_012365544.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BAMMC406_RS18485 628901..630541 + 1641 WP_012365545.1 acetolactate synthase large subunit -
BAMMC406_RS18490 630570..632003 + 1434 WP_012365546.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-94)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11793.45 Da        Isoelectric Point: 9.9728

>T22784 WP_012365544.1 NC_010552:c628577-628260 [Burkholderia ambifaria MC40-6]
MPYSAPTFSIRTTDVFEAWFAGLQDRVAQRRIQARIDRLSMGNPGDWKSAGSPVVEMRVDHGPGYRVYYVRRGTIWVILL
GGGDKSTQQADIRAAHAMLARLDLE

Download         Length: 318 bp

>T22784 NC_010552:c628577-628260 [Burkholderia ambifaria MC40-6]
ATGCCATACAGTGCACCAACATTCAGTATCCGGACCACCGACGTCTTCGAAGCGTGGTTTGCCGGCCTGCAGGATCGCGT
CGCGCAGCGCCGCATCCAGGCGCGCATCGACCGTCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAATGCGTGTCGATCACGGGCCCGGCTATCGCGTCTACTACGTCAGGCGCGGAACGATATGGGTGATCCTGCTC
GGCGGCGGCGACAAGTCGACGCAACAGGCGGACATCCGCGCCGCGCACGCGATGCTCGCGCGGCTCGATCTGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10700.14 Da        Isoelectric Point: 6.4770

>AT22784 WP_012365543.1 NC_010552:c628256-627957 [Burkholderia ambifaria MC40-6]
MDKIKTRPWDSAEYLKTDDDMADYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAHA

Download         Length: 300 bp

>AT22784 NC_010552:c628256-627957 [Burkholderia ambifaria MC40-6]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAGTACCTGAAAACCGACGACGACATGGCCGACTACTTCGAGGC
CTGTCTGCAGGAAGCCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCGCGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAGGCGCACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References