Detailed information of TA system TA022777

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 2759984..2761027
• Replicon: chromosome
• Accession: NC_010546
• Organism: Cyanothece sp. ATCC 51142

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: CCE_RS12730
• Protein ID: WP_009544623.1
• Coordinates: 2759984..2760556 (-)
• Length: 191 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: CCE_RS12735
• Protein ID: WP_009544622.1
• Coordinates: 2760557..2761027 (-)
• Length: 157 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCE_RS12715	2755904..2756851	+	948	WP_012361948.1	cation transporter	-
CCE_RS12720	2756897..2758369	-	1473	WP_009544625.1	FAD-binding oxidoreductase	-
CCE_RS12725	2758594..2759946	+	1353	WP_009544624.1	MATE family efflux transporter	-
CCE_RS12730	2759984..2760556	-	573	WP_009544623.1	PIN domain-containing protein	Toxin
CCE_RS12735	2760557..2761027	-	471	WP_009544622.1	helix-turn-helix domain-containing protein	Antitoxin
CCE_RS12740	2761117..2762256	-	1140	WP_009544621.1	DegT/DnrJ/EryC1/StrS family aminotransferase	-
CCE_RS12745	2762371..2763768	-	1398	WP_009544620.1	hypothetical protein	-
CCE_RS12750	2763813..2764289	-	477	WP_009544619.1	universal stress protein	-
CCE_RS12755	2764303..2765472	-	1170	WP_182670751.1	pyridoxal phosphate-dependent aminotransferase	-
CCE_RS12760	2765571..2765876	-	306	WP_009544617.1	DUF3181 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-114)

Antitoxin

• Helix-turn-helix domain, group 17 (85-130)

Sequences

Toxin

Protein

• Length: 191 a.a.
• Molecular weight: 21994.63 Da
• Isoelectric Point: 6.0131

>T22777 WP_009544623.1 NC_010546:c2760556-2759984 [Crocosphaera subtropica ATCC 51142]
MSSNFTALYDACVLYPAPLRDLLMQLALTDLFRARWTDTIHDEWIRNILKNRPDLTLEQLIKIKNLMNSHVRDCLITGYE
ELISSINLPDSDDRHVLAAAIKGQVDVIVTMNLKDFPSHVLDNYEIFVEHPDKFISNLIDLKPFKVAKAAETCRKRLKKP
PKSIDEYLEILLKQELPITVSMLRELSYEV

Nucleotide

• Length: 573 bp

>T22777 NC_010546:c2760556-2759984 [Crocosphaera subtropica ATCC 51142]
ATGTCCTCTAATTTTACTGCCCTTTATGATGCTTGTGTTTTGTATCCTGCACCGTTAAGAGATTTATTGATGCAGTTAGC
ATTAACTGACCTTTTTAGAGCGCGTTGGACTGATACAATTCATGATGAATGGATTCGTAATATTCTAAAAAATAGACCTG
ATTTAACCCTTGAACAGTTGATAAAAATTAAGAATTTAATGAATAGTCATGTTCGTGATTGTTTAATAACAGGTTATGAG
GAATTAATTTCCTCAATTAATTTACCAGATTCTGATGATCGTCATGTATTAGCAGCAGCTATAAAAGGTCAAGTTGATGT
TATTGTTACTATGAATCTTAAAGATTTTCCATCTCATGTTCTTGATAATTATGAAATTTTTGTAGAACATCCCGATAAGT
TTATTTCAAATTTAATTGATTTAAAACCTTTTAAAGTTGCAAAAGCAGCAGAAACTTGTCGAAAAAGATTAAAAAAACCG
CCTAAATCTATAGACGAATATTTAGAAATTTTACTCAAACAAGAATTACCAATTACGGTTTCAATGTTGCGAGAACTTTC
TTACGAAGTGTAA

Antitoxin

Protein

• Length: 157 a.a.
• Molecular weight: 17696.25 Da
• Isoelectric Point: 6.3390

>AT22777 WP_009544622.1 NC_010546:c2761027-2760557 [Crocosphaera subtropica ATCC 51142]
MTVSKTLNKPFIPSESEIKTAQESSRILASHLQSNHQSQTIKLLKNDSTEQVVEIPASAFHLLIDILTQMAQGNAITLIP
IHAELTTQEAADILNVSRPYVIKLLESGEIPFTKVGKHRRIRFEDIMNYKDNIDRKRSEVLDKLVEQAQELNMGYE

Nucleotide

• Length: 471 bp

>AT22777 NC_010546:c2761027-2760557 [Crocosphaera subtropica ATCC 51142]
ATGACCGTCTCAAAAACACTTAACAAACCATTCATTCCGTCTGAGTCAGAGATAAAAACTGCTCAGGAAAGTAGTCGCAT
TTTAGCGTCTCATCTTCAATCCAATCATCAATCTCAAACGATCAAACTGTTAAAAAATGATAGCACTGAACAAGTTGTTG
AAATACCTGCTAGTGCTTTTCATTTATTGATTGATATCTTAACTCAAATGGCACAAGGAAATGCAATAACTCTAATTCCT
ATTCATGCTGAGTTAACCACTCAAGAAGCTGCTGATATTTTGAATGTGTCTCGTCCTTATGTAATCAAATTACTGGAGTC
TGGAGAAATTCCTTTTACTAAAGTGGGAAAACATCGTCGTATTCGTTTTGAAGATATTATGAACTACAAAGATAATATTG
ATCGTAAGCGAAGTGAAGTATTAGATAAACTAGTAGAACAAGCACAAGAATTAAACATGGGTTATGAGTAA