Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1958662..1958807 Replicon chromosome
Accession NZ_CP089097
Organism Klebsiella pneumoniae strain EH13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1958698..1958800 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1958662..1958807 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSG42_RS09565 (LSG42_09565) 1953792..1955852 + 2061 WP_004151449.1 oligopeptidase B -
LSG42_RS09570 (LSG42_09570) 1955856..1956515 - 660 WP_002911407.1 exodeoxyribonuclease X -
LSG42_RS09575 (LSG42_09575) 1956594..1956824 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LSG42_RS09580 (LSG42_09580) 1956937..1957311 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LSG42_RS09585 (LSG42_09585) 1957315..1958184 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LSG42_RS09590 (LSG42_09590) 1958201..1958539 + 339 WP_002911404.1 YebY family protein -
- 1958662..1958807 - 146 - - Antitoxin
- 1958698..1958800 + 103 - - Toxin
LSG42_RS09595 (LSG42_09595) 1959175..1959318 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LSG42_RS09600 (LSG42_09600) 1959423..1960391 - 969 WP_004151446.1 VirK/YbjX family protein -
LSG42_RS09605 (LSG42_09605) 1960548..1961201 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
LSG42_RS09610 (LSG42_09610) 1961198..1961389 - 192 WP_002911395.1 YebW family protein -
LSG42_RS09615 (LSG42_09615) 1961487..1961726 - 240 WP_002911393.1 YebV family protein -
LSG42_RS09620 (LSG42_09620) 1961842..1963275 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227633 NZ_CP089097:1958698-1958800 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227633 NZ_CP089097:c1958807-1958662 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References