Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 859104..859963 | Replicon | chromosome |
Accession | NZ_CP089094 | ||
Organism | Microcystis aeruginosa FACHB-905 = DIANCHI905 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | A0A1X9LDD0 |
Locus tag | LRR78_RS04140 | Protein ID | WP_002742889.1 |
Coordinates | 859565..859963 (+) | Length | 133 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | A0A1X9LBQ1 |
Locus tag | LRR78_RS04135 | Protein ID | WP_002742890.1 |
Coordinates | 859104..859523 (+) | Length | 140 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LRR78_RS04115 (LRR78_04115) | 854832..855695 | - | 864 | WP_002742899.1 | WYL domain-containing protein | - |
LRR78_RS04120 (LRR78_04120) | 855794..857959 | + | 2166 | WP_084990033.1 | type I-D CRISPR-associated helicase Cas3' | - |
LRR78_RS04125 (LRR78_04125) | 858006..858248 | + | 243 | WP_002742893.1 | hypothetical protein | - |
LRR78_RS04130 (LRR78_04130) | 858594..858941 | + | 348 | WP_002742891.1 | hypothetical protein | - |
LRR78_RS04135 (LRR78_04135) | 859104..859523 | + | 420 | WP_002742890.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
LRR78_RS04140 (LRR78_04140) | 859565..859963 | + | 399 | WP_002742889.1 | DUF86 domain-containing protein | Toxin |
LRR78_RS04145 (LRR78_04145) | 859956..860414 | + | 459 | WP_036400372.1 | nucleotidyltransferase domain-containing protein | - |
LRR78_RS04150 (LRR78_04150) | 860500..860643 | + | 144 | WP_002742887.1 | hypothetical protein | - |
LRR78_RS04155 (LRR78_04155) | 860636..864082 | + | 3447 | WP_002742886.1 | type I-D CRISPR-associated protein Cas10d/Csc3 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 15324.59 Da Isoelectric Point: 4.6345
>T227625 WP_002742889.1 NZ_CP089094:859565-859963 [Microcystis aeruginosa FACHB-905 = DIANCHI905]
MNQYLAELSEYGSITLEDYRTLRERQLAIERLIQLIIQTGIDINYQILKCLDIESPNNARDALFQIVELGILEEHLAVQL
AESIKLRNLLVHLYKKIDPDIVHSSIANILRDYPRYQRSIVQFLDSLEAENG
MNQYLAELSEYGSITLEDYRTLRERQLAIERLIQLIIQTGIDINYQILKCLDIESPNNARDALFQIVELGILEEHLAVQL
AESIKLRNLLVHLYKKIDPDIVHSSIANILRDYPRYQRSIVQFLDSLEAENG
Download Length: 399 bp
>T227625 NZ_CP123008:c476204-475953 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA
Antitoxin
Download Length: 140 a.a. Molecular weight: 16307.78 Da Isoelectric Point: 5.1063
>AT227625 WP_002742890.1 NZ_CP089094:859104-859523 [Microcystis aeruginosa FACHB-905 = DIANCHI905]
MNRLVEKITAIVEKLPNLKLLILFGSRARREHRPDSDWDFAVLYEERSDQKDISSLLKIYTLLEQALEIPEDKIDVVDLK
ECSPILAHYVARDGQLLYERETGLFEGFKEKFLMNPEESKALYRQLRNNLEISLREKGV
MNRLVEKITAIVEKLPNLKLLILFGSRARREHRPDSDWDFAVLYEERSDQKDISSLLKIYTLLEQALEIPEDKIDVVDLK
ECSPILAHYVARDGQLLYERETGLFEGFKEKFLMNPEESKALYRQLRNNLEISLREKGV
Download Length: 420 bp
>AT227625 NZ_CP123008:c475956-475702 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X9LDD0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X9LBQ1 |