Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 2777017..2778275 | Replicon | chromosome |
Accession | NZ_CP089065 | ||
Organism | Pseudomonas aeruginosa strain UNC_PaerCF34 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | LSP20_RS13050 | Protein ID | WP_003123189.1 |
Coordinates | 2777520..2778275 (+) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | LSP20_RS13045 | Protein ID | WP_003086329.1 |
Coordinates | 2777017..2777385 (+) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LSP20_RS13025 (LSP20_13030) | 2773180..2773455 | + | 276 | WP_010792073.1 | zinc ribbon domain-containing protein | - |
LSP20_RS13030 (LSP20_13035) | 2773458..2773934 | - | 477 | WP_003112531.1 | hypothetical protein | - |
LSP20_RS13035 (LSP20_13040) | 2774109..2775602 | + | 1494 | WP_003086325.1 | aldehyde dehydrogenase family protein | - |
LSP20_RS13040 (LSP20_13045) | 2775658..2776944 | + | 1287 | WP_003123190.1 | FAD-binding oxidoreductase | - |
LSP20_RS13045 (LSP20_13050) | 2777017..2777385 | + | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
LSP20_RS13050 (LSP20_13055) | 2777520..2778275 | + | 756 | WP_003123189.1 | RES family NAD+ phosphorylase | Toxin |
LSP20_RS13055 (LSP20_13060) | 2779043..2780404 | + | 1362 | WP_003081943.1 | DNA recombination protein RmuC | - |
LSP20_RS13060 (LSP20_13065) | 2780559..2783102 | - | 2544 | WP_003123188.1 | acyl-homoserine-lactone acylase QuiP | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28267.46 Da Isoelectric Point: 8.3428
>T227596 WP_003123189.1 NZ_CP089065:2777520-2778275 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGMRLQAPPFSDHEAALTDIA
DYRAPQKLGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGMRLQAPPFSDHEAALTDIA
DYRAPQKLGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
>T227596 NZ_CP123000:c2992112-2991759 [Neorhizobium petrolearium]
ATGAGGCGGGGGGATATCTGGACGGTCGCGGGCGGCAAGGATTACGCGGGCAAACCGCGTCCGGTCGTGATCATGCAGGA
CGACAGTTTCGACGGGACGGATTCGATCACCGTCTGCGCCTTCACATCGGATGATACGGAAGCGCCGTTGTTTCGGCTTC
CCGTTGCCCCGGACGAGCGCAATGGCCTGCGGCTGTCTTCCCGCCTGATGGTGGACAAGATCACCACCGTCCCGAAATCG
AAGATCGGCGAGAAAGTCGGACGGCTGGACGACGAAGATATAGTGCGACTCAATCAGGCGATGCTGGTTTTTCTCGGGCT
TGCCGTGTCGCCAAGGGTAAGGGGAGAGGCTTGA
ATGAGGCGGGGGGATATCTGGACGGTCGCGGGCGGCAAGGATTACGCGGGCAAACCGCGTCCGGTCGTGATCATGCAGGA
CGACAGTTTCGACGGGACGGATTCGATCACCGTCTGCGCCTTCACATCGGATGATACGGAAGCGCCGTTGTTTCGGCTTC
CCGTTGCCCCGGACGAGCGCAATGGCCTGCGGCTGTCTTCCCGCCTGATGGTGGACAAGATCACCACCGTCCCGAAATCG
AAGATCGGCGAGAAAGTCGGACGGCTGGACGACGAAGATATAGTGCGACTCAATCAGGCGATGCTGGTTTTTCTCGGGCT
TGCCGTGTCGCCAAGGGTAAGGGGAGAGGCTTGA
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT227596 WP_003086329.1 NZ_CP089065:2777017-2777385 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
>AT227596 NZ_CP123000:c2992333-2992109 [Neorhizobium petrolearium]
ATGGTTTCCGCATCAAAGCCGAAGCCTACGCGCGTAAAGGTGGGCGAACATCGCGCCCGGCTGCGTGCTCAAGGTCTGCG
TCCGATCCAAATTTGGGTGCCGGACGTGCGTGCGCCCTCATTCAAGGTCGAGGCTCACCGCCAGTCGCTTGCGGTCGCGG
CAAGCGCACAGGCGGCGGACGATCAGGCGTTTATCGATGCCGTCTCCGATTGGGGCGATGAATGA
ATGGTTTCCGCATCAAAGCCGAAGCCTACGCGCGTAAAGGTGGGCGAACATCGCGCCCGGCTGCGTGCTCAAGGTCTGCG
TCCGATCCAAATTTGGGTGCCGGACGTGCGTGCGCCCTCATTCAAGGTCGAGGCTCACCGCCAGTCGCTTGCGGTCGCGG
CAAGCGCACAGGCGGCGGACGATCAGGCGTTTATCGATGCCGTCTCCGATTGGGGCGATGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|