Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2452811..2453494 Replicon chromosome
Accession NC_010513
Organism Xylella fastidiosa M12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XFASM12_RS10825 Protein ID WP_004086858.1
Coordinates 2452811..2453239 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XFASM12_RS10830 Protein ID WP_004086856.1
Coordinates 2453240..2453494 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFASM12_RS10795 2449365..2450126 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
XFASM12_RS10820 2451327..2452721 + 1395 WP_012338158.1 hypothetical protein -
XFASM12_RS10825 2452811..2453239 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
XFASM12_RS10830 2453240..2453494 - 255 WP_004086856.1 hypothetical protein Antitoxin
XFASM12_RS10835 2453619..2454161 + 543 WP_012338159.1 hypothetical protein -
XFASM12_RS10840 2454482..2454855 - 374 Protein_2109 DUF596 domain-containing protein -
XFASM12_RS10845 2454867..2455199 - 333 WP_076613248.1 DUF769 domain-containing protein -
XFASM12_RS10850 2455371..2455766 - 396 WP_193329301.1 DUF596 domain-containing protein -
XFASM12_RS10855 2455773..2456126 - 354 Protein_2112 DUF769 domain-containing protein -
XFASM12_RS10860 2456304..2456687 - 384 WP_004086848.1 DUF596 domain-containing protein -
XFASM12_RS10865 2456692..2457729 - 1038 WP_012338161.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T22758 WP_004086858.1 NC_010513:c2453239-2452811 [Xylella fastidiosa M12]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T22758 NC_010513:c2453239-2452811 [Xylella fastidiosa M12]
ATGATTGTCTTGGATACCAATGTTGTTTCCGAAGCAATGAAACCCGAGCCGGATGCAGCAGTCCGAACCTGGCTCAACGA
GCAGATGAGCGTCACGTTGTACCTATCCAGTGTGACGTTATCTGAACTGTTGTTTGGAATCGCAGTGTTGCCCACAAGTA
AGCGCAAGGACATGTTGGCTCGTACCCTTGATGGCTTGCTTGATCTGTTCAATGAACGGGTGTTGCCGTTCGATACGGAC
GCGGCACGCCACTATGCTGAACTGGCAGTGAAAGCGAGAAACAATGGGCGCGGCTTTCCCACACCGGATGGCTATATCGC
GGCAATTGCTGCATCACGAGGTTACATAGTAGCTTCCCGCGACACCTCAGCCTATGAGTCAAGTGGTGTGCAAGTCATCA
ATCCGTGGCAATACAGCAAACAAACATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT22758 WP_004086856.1 NC_010513:c2453494-2453240 [Xylella fastidiosa M12]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT22758 NC_010513:c2453494-2453240 [Xylella fastidiosa M12]
ATGGCCATGTTGACAGTGCGTAATTTGCCTGATGAAGTCCATCGCGCCTTGCGGGTTCGAGCCGCCACACACGGCCGCAG
TACAGAAGCGGAAGTACGTGAGATTTTAACGAACATAGTCAAGCCGGATGAGCGTGTTCGCATTGGCGATGCCTTGGCTA
TCCTGGGACGCGAGATCGGACTAAATAACGAGGATTTCACGACCTTTGATAAGGTGCGAGACAAGACGCAGGCCGAGCCG
ATGAGATTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References